China Factory Direct
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| CAS number | 178312-47-5 |
| Product name | ETHYL 4,4-DIFLUOROCYCLOHEXANECARBOXYLATE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty Grade |
| Packaging | 25L/drum |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Potential drug intermediate for synthesizing fluorinated cyclohexyl-containing active pharmaceutical ingredients (APIs) | Used as a chiral building block in coupling, amidation, or reduction reactions to prepare candidate compounds targeting G protein-coupled receptors (GPCRs) or metabolic enzyme inhibitors |
| Agrochemicals | Structural modification intermediate for novel fluorinated agrochemicals | Introduced as a 4,4-difluorocyclohexyl moiety to enhance lipophilicity, metabolic stability, and target-binding selectivity in insecticide or fungicide molecular design |
| Materials Science | Functional monomer precursor for high-performance fluorinated polymers | After hydrolysis and activation, incorporated into condensation polymerization or ring-opening copolymerization to produce weather-resistant, hydrophobic specialty engineering plastics or side-chain-modified liquid crystal materials |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at 210 nm. |
| Related Substances | HPLC-DAD | Separation and identification of impurities using gradient HPLC with diode-array detection; impurities reported as area percent relative to main peak. |
| Residual Solvents | GC-FID | Volatile organic solvents quantified by gas chromatography with flame ionization detection using headspace sampling and internal standard calibration. |
| Water Content | Karl Fischer Titration | Coulometric or volumetric titration based on the reaction of iodine with water in a pyridine-methanol solvent system. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (e.g., Pb, Cd, Hg, As) after acid digestion, using inductively coupled plasma mass spectrometry. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of chloride anion on an anion-exchange column with suppressed conductivity detection. |
| Residual Catalyst (Pd) | ICP-OES | Quantification of palladium residue after microwave-assisted acid digestion using inductively coupled plasma optical emission spectroscopy. |
| Melting Point | Capillary Melting Point Apparatus | Determination of solid-to-liquid phase transition temperature using calibrated capillary apparatus per USP <741>. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation of plane-polarized light at 20 degrees C using sodium D-line (589 nm) to confirm chiral integrity. |
| Loss on Drying | Gravimetric Analysis | Mass loss measured after drying under controlled temperature and vacuum per USP <731>, reported as weight percent. |
| Particle Size Distribution | Laser Diffraction | Size distribution analysis of dry powder via Mie scattering theory using a laser diffraction particle size analyzer. |
| Microbial Limits | Membrane Filtration | Enumeration of aerobic microorganisms and absence testing for specified pathogens per USP <61> and <62>. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 128°C - 132°C |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
| Acid Value (mg KOH/g) | 185 - 195 mg KOH/g |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.