Cyclohexanemethanol, 4,4-difluoro- (9CI) Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 178312-48-6 |
| Product name | Cyclohexanemethanol, 4,4-difluoro- (9CI) |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Material GradeSpecialty GradeIndustrial Grade |
| Packaging | 25L/drum |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Cyclohexanemethanol, 4,4-difluoro- (9CI)
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Cyclohexanemethanol, 4,4-difluoro- (9CI) Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Cyclohexanemethanol, 4,4-difluoro- (9CI)
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Synthesis of fluorinated cyclohexyl-containing drug molecules, such as targeted protein degraders (PROTACs) and G protein-coupled receptor (GPCR) modulators | Used as a chiral building block in coupling reactions (e.g., Mitsunobu, esterification, carbamate formation) or further oxidized to prepare corresponding aldehyde/acid derivatives |
| Organic Synthesis | Highly selective fluorinated alicyclic alcohol building block for constructing lead compounds with controlled steric bulk and enhanced metabolic stability | Subjected to multi-step functional group transformations, including protection (e.g., TBSCl), activation (e.g., MsCl/TsCl), nucleophilic substitution, or reductive amination |
| Materials Science (Research Stage) | Potential liquid crystal monomer or side-chain modifier for specialty polymers, used to tune mesophase behavior and thermal stability | Employed as an initiator for ring-opening polymerization (e.g., propylene oxide) or condensed with diisocyanates to synthesize fluorinated polyurethanes |
Manufacturing Quality Control of Cyclohexanemethanol, 4,4-difluoro- (9CI)
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | GC-FID or GC-MS | Quantitative determination by comparison of peak area against a certified reference standard using gas chromatography with flame ionization or mass spectrometric detection. |
| Water Content | Karl Fischer Titration | Electrochemical titration based on the reaction of iodine with water in a controlled anhydrous environment. |
| Residual Solvents | Headspace GC-FID | Separation and quantification of volatile organic solvents using gas chromatography after equilibration in sealed headspace vials. |
| Chloride Impurity | Ion Chromatography (IC) | Separation and conductivity-based detection of chloride anions after ion exchange column separation. |
| Heavy Metals (Pb, Cd, Hg, As) | ICP-MS | Multi-element detection via plasma ionization and mass spectrometric analysis for trace metal quantification. |
| Acid Value | Acid-Base Titration (NaOH in ethanol) | Neutralization of acidic impurities with standardized sodium hydroxide solution using phenolphthalein indicator. |
| Optical Rotation | [alpha]D Measurement | Determination of specific rotation using polarized light at 589 nm to assess chiral purity and enantiomeric excess. |
| Residue on Ignition | Gravimetric Analysis | Weighing of non-volatile residue remaining after high-temperature ashing in a muffle furnace. |
| Related Substances | HPLC-UV | Separation and UV detection of structurally related impurities using reversed-phase liquid chromatography. |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity against specified standards under controlled lighting conditions. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid transitions to liquid using calibrated capillary method. |
| Density | Digital Density Meter | Measurement of mass per unit volume at specified temperature using oscillating U-tube principle. |
Technical Specifications of Cyclohexanemethanol, 4,4-difluoro- (9CI)
| Test Item | Specification |
|---|---|
| Appearance | Colorless liquid |
| Purity | >=98.0% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Refractive Index (n20/D) | 1.465–1.475 |
| Relative Density (20°C/25°C) | 1.08–1.12 g/cm³ |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Cyclohexanemethanol, 4,4-difluoro- (9CI)
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Cyclohexanemethanol, 4,4-difluoro- (9CI)
Safety Information of Cyclohexanemethanol, 4,4-difluoro- (9CI)
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of Cyclohexanemethanol, 4,4-difluoro- (9CI)
Industrial Cyclohexanemethanol, 4,4-difluoro- (9CI) Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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