H-ASP(OTBU)-OTBU HCL Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 1791-13-5 |
| Product name | H-ASP(OTBU)-OTBU HCL |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for H-ASP(OTBU)-OTBU HCL
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk H-ASP(OTBU)-OTBU HCL Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of H-ASP(OTBU)-OTBU HCL
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Protecting reagent for the L-aspartic acid structural unit in synthesis of antiviral agents (e.g., adefovir dipivoxil), peptide-based therapeutics, and chiral drugs | Used as a selective dual-protecting reagent for the aspartic acid side-chain (β-carboxyl) and α-carboxyl groups in solid-phase or solution-phase peptide synthesis; the hydrochloride salt form facilitates crystallization, purification, and storage, with subsequent removal of the tert-butyl protecting group using trifluoroacetic acid (TFA) |
| Organic Synthesis | Chiral building block for preparing asymmetric catalyst ligands and functionalized amino acid derivatives | Undergoes N-alkylation or acylation with acyl chlorides, anhydrides, and other electrophiles under basic conditions; the tert-butyl ester group provides steric bulk to control regioselectivity and stereoselectivity |
| Biochemical Research | Controlled conjugation platform for site-specific protein/peptide modification, fluorescent labeling, and enzyme inhibitor design | Conjugated via its free α-amino group with NHS-activated fluorescent dyes (e.g., FITC), biotin, or PEG derivatives; the tert-butyl–protected β-carboxyl group prevents side reactions, followed by acid-mediated deprotection after conjugation |
Manufacturing Quality Control of H-ASP(OTBU)-OTBU HCL
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC with UV detection | Quantification based on peak area comparison against a certified reference standard using reversed-phase chromatography. |
| Chiral Purity | Chiral HPLC | Separation of enantiomers on a chiral stationary phase, with detection by UV to determine L-isomer content. |
| Residual Solvents | Gas Chromatography (GC) with FID | Volatile organic solvents are separated by capillary column and quantified by flame ionization detection. |
| Water Content | Karl Fischer Titration | Electrochemical titration where iodine reacts stoichiometrically with water in a methanol-based reagent. |
| Heavy Metals | ICP-OES | Multi-element detection after acid digestion, based on characteristic atomic emission spectra. |
| Chloride Impurity | Ion Chromatography (IC) | Separation of anions on an ion-exchange column followed by conductivity detection. |
| Residual tert-Butyl Alcohol | GC-FID | Direct injection and quantification of residual t-butanol using internal standard calibration. |
| pH (1% aqueous solution) | pH meter measurement | Potentiometric measurement of hydrogen ion activity in a standardized aqueous solution. |
| Melting Point | Capillary melting point apparatus | Thermal transition observed as solid-to-liquid phase change under controlled heating rate. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light induced by chiral molecules in solution. |
| Appearance | Visual inspection | Assessment of physical state, color, and clarity against defined reference standards under controlled lighting. |
| Loss on Drying | Gravimetric analysis | Mass loss measured after drying at specified temperature and time under vacuum or nitrogen purge. |
Technical Specifications of H-ASP(OTBU)-OTBU HCL
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Melting Point | 148-152°C |
| Optical Rotation | +6.0 to +8.0° (c=1, in 1M HCl) |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of H-ASP(OTBU)-OTBU HCL
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of H-ASP(OTBU)-OTBU HCL
Packaging of H-ASP(OTBU)-OTBU HCL
Industrial H-ASP(OTBU)-OTBU HCL Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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