4-N-Boc-aminocyclohexanone Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 179321-49-4 |
| Product name | 4-N-Boc-aminocyclohexanone |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Material GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4-N-Boc-aminocyclohexanone
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4-N-Boc-aminocyclohexanone Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4-N-Boc-aminocyclohexanone
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Critical intermediate for synthesizing active pharmaceutical ingredients (APIs) containing an aminocyclohexyl moiety (e.g., kinase inhibitors, G protein-coupled receptor modulators) | After Boc deprotection via acidolysis (e.g., TFA/DCM) under inert atmosphere, undergoes condensation, reductive amination, or related reactions with acyl chlorides, isocyanates, or aldehydes/ketones to construct the target molecular scaffold |
| Organic Synthesis | Stereoselective synthesis precursor for chiral cyclohexylamine derivatives | Serves as substrate in asymmetric reduction, asymmetric α-functionalization, or cycloaddition reactions; the Boc group provides steric bulk and stability, facilitating subsequent selective transformations |
| Materials Science | Functional monomer for synthesizing stimuli-responsive polymers bearing cyclohexylamine side chains | Incorporated into the polymer backbone via ring-opening polymerization or free-radical copolymerization; the Boc group can be selectively removed during post-polymerization processing to unmask the primary amine, enabling pH responsiveness or crosslinking functionality |
Manufacturing Quality Control of 4-N-Boc-aminocyclohexanone
| Test Item | Common Test Method | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the sample's color and physical state (e.g., white to off-white crystals or powder), checking for foreign matter, caking, or other physical characteristics. |
| Purity | High-Performance Liquid Chromatography (HPLC) | Use a reversed-phase column with a suitable mobile phase (e.g., acetonitrile-water/phosphate buffer) to separate components; quantify main peak purity and assess impurity levels using a UV detector. |
| Related Substances | HPLC (Gradient Elution) | Employ a gradient elution program to separate potential impurities (e.g., starting materials, by-products, degradation products); calculate individual impurity levels using area normalization or external standard methods. |
| Moisture Content | Karl Fischer Titration | Use Karl Fischer reagent to react quantitatively with water in the sample; determine moisture content via potentiometric or volumetric titration to ensure product stability. |
| Residual Solvents | Gas Chromatography (GC) | Use headspace or direct injection, separate with a DB-624 or similar capillary column, and quantify residual organic solvents (e.g., methanol, ethyl acetate, dichloromethane) using an FID detector. |
| Melting Point | Capillary Melting Point Determination | Determine the melting temperature range using a digital melting point apparatus to assess crystalline form and purity consistency. |
| Optical Rotation (if applicable) | Polarimetry | For chiral compounds or those with optically active impurities, measure specific optical rotation to control stereochemical purity. |
| Structural Confirmation | Nuclear Magnetic Resonance (NMR), Infrared Spectroscopy (IR), Mass Spectrometry (MS) | NMR (¹H, ¹³C) confirms molecular structure; IR verifies characteristic functional groups (e.g., carbonyl, Boc group); MS confirms molecular weight and fragmentation patterns. |
| pH Value (in solution) | pH Meter Measurement | Prepare a solution of defined concentration in water or appropriate solvent and measure pH to evaluate acid-base stability or impact on formulation. |
| Residue on Ignition / Sulfated Ash | Gravimetric Method | Weigh inorganic residue after high-temperature ignition of the sample to control levels of metal catalysts or inorganic salts. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or ICP-MS | Digest the sample and measure residual heavy metal elements (e.g., lead, cadmium, mercury, arsenic) to comply with pharmacopoeial or ICH Q3D limits. |
Technical Specifications of 4-N-Boc-aminocyclohexanone
| Test Item | Specification |
|---|---|
| Appearance | Off-white solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 112–116°C |
| Identification (NMR) | Conforms to reference spectrum |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4-N-Boc-aminocyclohexanone
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4-N-Boc-aminocyclohexanone
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Industrial 4-N-Boc-aminocyclohexanone Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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