China Factory Direct
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| CAS number | 179688-01-8 |
| Product name | 6-Methoxy-7-benzyloxyquinazolin-4-one |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Serves as a key intermediate in the synthesis of tyrosine kinase inhibitor anticancer drugs (e.g., erlotinib) | Organic synthesis, condensation reaction, purification |
| Pharmaceutical R&D | Used for new drug molecule screening and structural modification to investigate the biological activity of quinazoline derivatives | Laboratory-scale synthesis, bioactivity testing |
| Fine Chemicals | Production of high-value quinazoline compounds for supply to pharmaceutical manufacturers or research institutions | Multi-step synthesis, crystallization, drying |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at 254 nm. |
| Related Substances | HPLC-UV | Separation and quantification of impurities relative to the main peak using gradient HPLC with UV detection. |
| Residual Solvents | GC-FID | Identification and quantification of volatile organic solvents based on retention time and flame ionization response. |
| Water Content | Karl Fischer Titration | Electrochemical titration measuring water via iodine-sulfur dioxide reaction in anhydrous methanol-based medium. |
| Heavy Metals | ICP-OES | Multi-element detection of toxic metals (e.g., Pb, Cd, Hg, As) after acid digestion and plasma excitation. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of chloride ions using suppressed conductivity detection. |
| Sulfated Ash | Gravimetric Analysis | Residue mass measurement after high-temperature incineration of sample in sulfuric acid medium. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition detection via optical observation of solid-to-liquid phase change under controlled heating. |
| Loss on Drying | Thermogravimetric Analysis (TGA) | Mass loss measurement upon controlled heating to determine volatile content including moisture and solvents. |
| Optical Rotation | Polarimetry | Measurement of plane-polarized light rotation angle to assess chiral purity and identity. |
| Particle Size Distribution | Laser Diffraction | Analysis of scattered laser light intensity to determine volumetric particle size distribution. |
| Microbial Limits | Membrane Filtration and Plate Count | Enumeration of aerobic mesophilic microorganisms following filtration and incubation on nutrient agar. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline solid |
| Purity | >=98.0% (LC-MS) |
| Melting Point | 215–219 °C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.