6-Hydroxy-7-methoxy-3,4-dihydroquinazolin-4-one Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 179688-52-9 |
| Product name | 6-Hydroxy-7-methoxy-3,4-dihydroquinazolin-4-one |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Reagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 6-Hydroxy-7-methoxy-3,4-dihydroquinazolin-4-one
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 6-Hydroxy-7-methoxy-3,4-dihydroquinazolin-4-one Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 6-Hydroxy-7-methoxy-3,4-dihydroquinazolin-4-one
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Intermediate for synthesizing biologically active quinazoline compounds | Used as a key intermediate in multi-step organic synthesis to construct the core structure of target drug molecules |
| Chemical Research | Organic synthesis reagent for developing novel quinazoline derivatives | Applied in laboratory-scale substitution and cyclization reactions to optimize reaction conditions for target product formation |
Manufacturing Quality Control of 6-Hydroxy-7-methoxy-3,4-dihydroquinazolin-4-one
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at 254 nm. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC with UV detection; identification based on retention time matching and threshold limits per ICH Q3B. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify volatile organic solvents according to ICH Q3C guidelines. |
| Water Content | Karl Fischer Titration | Electrochemical titration using iodine, sulfur dioxide, and pyridine-based reagent to determine water content by stoichiometric reaction. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (e.g., Pb, Cd, Hg, As) after acid digestion, using inductively coupled plasma mass spectrometry for sub-ppb sensitivity. |
| Chloride Impurity | Ion Chromatography | Separation and conductivity detection of chloride anions in aqueous extract using suppressed ion chromatography with standardized calibration. |
| Sulfated Ash | Gravimetric Analysis | Ignition of sample at 700-800 C followed by weighing of non-volatile inorganic residue after treatment with sulfuric acid. |
| Melting Point | Capillary Melting Point Apparatus | Thermal determination of solid-to-liquid phase transition using calibrated capillary apparatus per USP <741>. |
| Optical Rotation | Polarimetry | Measurement of specific rotation using sodium D-line light to assess chiral purity and identity; requires dissolution in specified solvent. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry or wet dispersed sample via light scattering pattern to determine D10, D50, D90 values per ISO 13320. |
| Microbial Limits | Membrane Filtration and Culture | Enumeration of aerobic microorganisms and detection of specified pathogens (e.g., E. coli, S. aureus) using selective agar media and incubation. |
| pH of Aqueous Suspension | Potentiometric pH Measurement | Determination of hydrogen ion activity in a defined suspension (e.g., 1% w/v in water) using calibrated glass electrode pH meter. |
Technical Specifications of 6-Hydroxy-7-methoxy-3,4-dihydroquinazolin-4-one
| Test Item | Specification |
|---|---|
| Appearance | Off-white crystalline solid |
| Purity | >=98.0% (HPLC) |
| Total Impurities | <=2.0% (HPLC) |
| Single Impurity | <=0.5% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 248–252°C |
| Identification (NMR) | Conforms to reference standard |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 6-Hydroxy-7-methoxy-3,4-dihydroquinazolin-4-one
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 6-Hydroxy-7-methoxy-3,4-dihydroquinazolin-4-one
Safety Information of 6-Hydroxy-7-methoxy-3,4-dihydroquinazolin-4-one
| Pictograms |  |
| Signal Word | Danger |
| Safety Data Sheet | |
Packaging of 6-Hydroxy-7-methoxy-3,4-dihydroquinazolin-4-one
Industrial 6-Hydroxy-7-methoxy-3,4-dihydroquinazolin-4-one Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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