(4-Cyclopropyl-6-methoxypyrimidin-5-yl)boronic acid Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 1798304-51-4 |
| Product name | (4-Cyclopropyl-6-methoxypyrimidin-5-yl)boronic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical GradeReagent Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for (4-Cyclopropyl-6-methoxypyrimidin-5-yl)boronic acid
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk (4-Cyclopropyl-6-methoxypyrimidin-5-yl)boronic acid Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of (4-Cyclopropyl-6-methoxypyrimidin-5-yl)boronic acid
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate in the synthesis of antitumor drugs | Used in Suzuki coupling reactions |
| Pharmaceutical R&D | Biologically active molecular probe | Applied in boronic esterification reactions |
| Agrochemicals | Intermediate for developing novel agrochemical compounds | Applied in coupling reactions to synthesize target molecules |
| Chemical Research | Building block in organic synthesis | Applied in cross-coupling reactions |
Manufacturing Quality Control of (4-Cyclopropyl-6-methoxypyrimidin-5-yl)boronic acid
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Appearance and Physical Properties | Visual Inspection / Physical Observation | Visually inspect the sample's color, state (such as white to off-white crystalline powder), and presence of foreign matter to initially assess its physical purity and consistency. |
| Identification | Proton Nuclear Magnetic Resonance (¹H NMR) Infrared Spectroscopy (IR) Mass Spectrometry (MS) |
Confirm characteristic hydrogen signals in ¹H NMR (such as cyclopropyl, methoxy, pyrimidine ring hydrogens); identify functional groups in IR (such as B–OH, C=O, C–O); and verify molecular ion peaks (e.g., [M+H]⁺ or [M−H]⁻) in MS to confirm the compound structure comprehensively. |
| Purity / Related Substances | High-Performance Liquid Chromatography (HPLC) | Use a reversed-phase C18 column with gradient elution of water and organic solvents (e.g., acetonitrile or methanol), and detect with a UV detector (typically 210–260 nm). Calculate the main component area normalization purity and evaluate organic impurity content. |
| Residual Solvents | Gas Chromatography (GC) | Detect residual organic solvents (such as methanol, ethanol, dichloromethane, THF) during synthesis or purification according to ICH Q3C guidelines using headspace-GC/FID or GC/MS. |
| Water Content | Karl Fischer Titration | Determine the water content using volumetric or coulometric methods to ensure it is within the specified limit (usually ≤1.0%), to prevent hydrolysis or degradation of boronic acid derivatives. |
| Ignited Residue / Ash Content | High-Temperature Incineration | Incinerate the sample at high temperature (e.g., 600–800°C) until constant weight to determine the content of inorganic residues, used to evaluate inorganic impurities or metal catalyst residue levels. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or Inductively Coupled Plasma Mass Spectrometry (ICP-MS) |
Detect heavy metal residues such as lead, arsenic, cadmium, and mercury according to pharmacopoeia methods to ensure compliance with ICH Q3D element impurity control requirements. |
| Boron Content | Inductively Coupled Plasma Optical Emission Spectrometry (ICP-OES) or Titration Method |
Quantitatively determine total boron content using ICP-OES to verify the presence and content of boron in the target compound (approximately 7.5%), which can also assist in assessing purity. |
Technical Specifications of (4-Cyclopropyl-6-methoxypyrimidin-5-yl)boronic acid
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 185–190°C |
| Residue on Ignition | <=0.2% |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of (4-Cyclopropyl-6-methoxypyrimidin-5-yl)boronic acid
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of (4-Cyclopropyl-6-methoxypyrimidin-5-yl)boronic acid
Safety Information of (4-Cyclopropyl-6-methoxypyrimidin-5-yl)boronic acid
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of (4-Cyclopropyl-6-methoxypyrimidin-5-yl)boronic acid
Industrial (4-Cyclopropyl-6-methoxypyrimidin-5-yl)boronic acid Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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