China Factory Direct
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| CAS number | 1800300-79-1 |
| Product name | (R)-Methyl 2-amino-3-methoxypropanoate hydrochloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Used in the asymmetric synthesis of chiral pharmaceuticals, including β-blockers, antihypertensive agents, and neuroactive compounds | Applied as a chiral amino alcohol precursor to construct molecular chiral centers via multi-step reactions such as reduction, cyclization, or coupling |
| Organic Synthesis | Used as a chiral building block for preparing complex chiral molecules containing methoxy and amino functional groups | Employed as a starting material in palladium-catalyzed cross-coupling, enzymatic kinetic resolution, or asymmetric hydrogenation |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification using reverse-phase HPLC with UV detection at 210 nm, comparing peak area to a certified reference standard. |
| Enantiomeric Excess (ee) | Chiral HPLC | Separation of (R)- and (S)-enantiomers on a chiral stationary phase, with UV detection and calculation of ee from peak areas. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine generated in situ to react stoichiometrically with water in the sample. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection, quantifying common solvents (e.g., methanol, dichloromethane) against calibration standards. |
| Heavy Metals | ICP-OES | Multi-element determination after acid digestion by measuring atomic emission intensities of metals (e.g., Pb, Cd, Ni) in plasma. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of chloride anion using suppressed conductivity detection with a carbonate/bicarbonate eluent. |
| Related Substances | HPLC-UV | Detection and quantification of structurally related impurities using gradient reverse-phase HPLC with UV detection. |
| Optical Rotation | [alpha]D Measurement | Determination of specific optical rotation using a polarimeter at 20 C and sodium D-line (589 nm) in specified solvent and concentration. |
| pH (1% aqueous solution) | Potentiometric pH Measurement | Measurement of hydrogen ion activity using calibrated glass electrode in a 1% w/v aqueous solution at 25 C. |
| Residue on Ignition | Gravimetric Analysis | Weighing residue remaining after incineration at 700-800 C, representing inorganic ash content. |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity against defined standards under controlled lighting conditions. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range over which solid-to-liquid phase transition occurs, using calibrated capillary method. |
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Optical Rotation | -10.0 ± 2.5 ° (c=1, in methanol) |
| Melting Point | 128–132 °C |
| Identification (NMR) | Consistent with structure |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.