bupivacaine hydrochloride Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 18010-40-7 |
| Product name | bupivacaine hydrochloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for bupivacaine hydrochloride
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk bupivacaine hydrochloride Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of bupivacaine hydrochloride
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Local anesthetic | Used for surgical anesthesia and postoperative analgesia |
| Pharmaceuticals | Nerve block agent | Applied in the treatment of chronic pain |
| Pharmaceuticals | Epidural anesthesia | Applied for analgesia during labor or surgery |
| Pharmaceuticals | Local infiltration anesthesia | Applied for intraoperative and postoperative local analgesia |
| Pharmaceuticals | Intra-articular injection analgesic | Used for pain management following orthopedic surgery |
Manufacturing Quality Control of bupivacaine hydrochloride
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Identification | Infrared Spectroscopy (IR) | Compare the infrared spectrum of the test sample with that of the standard under the same conditions, by analyzing the position and consistency of absorption peaks to confirm the chemical structure. |
| High-Performance Liquid Chromatography (HPLC) | Compare the chromatographic behavior of the test sample with that of the reference standard by retention time to confirm the consistency of components. | |
| Content Determination | High-Performance Liquid Chromatography (HPLC) | Use a reversed-phase column (e.g., C18) with a UV detector (typically 210–280 nm), and quantify the main component using external standard or internal standard methods. |
| Non-aqueous Titration | Titrate in an acetic acid medium using a standard solution of perchloric acid, suitable for content determination of raw materials. | |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Separate and detect organic impurities such as synthetic intermediates and degradation products using gradient or isocratic elution, and calculate the content of each impurity and total impurities. |
| Residual Solvents | Gas Chromatography (GC) | Detect residual organic solvents (e.g., methanol, acetone, dichloromethane) during production according to ICH guidelines, using headspace sampling. |
| Water Content | Karl Fischer Titration | Accurately determine the water content in the sample, suitable for quality control of moisture-sensitive raw materials. |
| Solution Clarity and Color | Visual Colorimetry / Spectrophotometry | Dissolve the sample in a specified solvent and compare its clarity and color with a standard color solution to assess compliance with specifications. |
| pH Value | pH Meter Method | Prepare the sample as a solution of a certain concentration and measure its pH value using a calibrated pH meter. |
| Residue on Ignition | Ignition Residue Test | After high-temperature ignition, weigh the residue to determine the total amount of inorganic impurities. |
| Heavy Metals | Sulfide Colorimetry (e.g., Chinese Pharmacopoeia method) | Under specific pH conditions, heavy metals react with sulfides to form colored precipitates, which are compared with standard lead solutions to determine the limit. |
| Polymorphic Analysis (if applicable) | X-ray Powder Diffraction (XRPD) | Used to identify different polymorphic forms and ensure consistency of polymorphic form between batches, which affects solubility and stability. |
| Particle Size Distribution (if for injection) | Laser Diffraction | Determine the particle size distribution of the raw material or formulation, especially crucial for suspensory injectables. |
Technical Specifications of bupivacaine hydrochloride
| Test Item | Specification |
|---|---|
| Appearance | White to almost white powder |
| Purity | >=98.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 236°C to 240°C |
| Total Impurities | <=2.0% (HPLC) |
| Single Impurity | <=0.5% (HPLC) |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of bupivacaine hydrochloride
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of bupivacaine hydrochloride
Packaging of bupivacaine hydrochloride
Industrial bupivacaine hydrochloride Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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