3-N-FMOC-3-PHENYLPROPIONIC ACID Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 180181-93-5 |
| Product name | 3-N-FMOC-3-PHENYLPROPIONIC ACID |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 3-N-FMOC-3-PHENYLPROPIONIC ACID
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 3-N-FMOC-3-PHENYLPROPIONIC ACID Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 3-N-FMOC-3-PHENYLPROPIONIC ACID
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Synthesis | Used as an amino-protecting group in the preparation of peptide synthesis intermediates | Applied in peptide synthesis to selectively protect amino groups via the fluorenylmethyloxycarbonyl (Fmoc) moiety, enabling stepwise chain assembly; this compound serves as the Fmoc derivative of 3-amino-3-phenylpropanoic acid for constructing peptides or drug molecules with defined structures |
| Bioconjugation Reagents | Used in conjugation reactions between proteins, peptides, and other molecules | Applied to achieve covalent intermolecular linkage via amide bond formation between its carboxyl group and amine-containing compounds; commonly used in antibody–drug conjugate (ADC) development and probe labeling |
| Chemical Intermediate | Synthesized into non-natural amino acids or functionalized molecules bearing aromatic side chains | Applied in the construction of functional molecules containing the phenylpropanoic acid scaffold through deprotection followed by subsequent functional group transformations; used in novel drug discovery and materials chemistry |
Manufacturing Quality Control of 3-N-FMOC-3-PHENYLPROPIONIC ACID
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by comparison of peak area against a certified reference standard using reversed-phase chromatography and UV detection at 260 nm. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient reversed-phase HPLC with UV detection; identification based on retention time matching and threshold limits per ICH Q3A/B. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify volatile organic solvents (e.g., DMF, DCM, methanol) against calibrated standards. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine trace water content based on stoichiometric electrochemical reaction. |
| Optical Rotation | [alpha]D Measurement | Measurement of specific optical rotation using a polarimeter at 20 degrees C and sodium D-line (589 nm) to confirm chiral integrity and enantiomeric purity. |
| Heavy Metals | ICP-MS | Quantitative determination of elemental impurities (e.g., Pb, Cd, Hg, As) after acid digestion, using inductively coupled plasma mass spectrometry for sub-pptr sensitivity. |
| Chloride Content | Ion Chromatography | Separation and quantification of chloride ions using suppressed conductivity detection after aqueous extraction and filtration. |
| Residue on Ignition | Gravimetric Analysis | Determination of inorganic ash content by ignition at 700-800 degrees C followed by precise weighing of residual inorganic material. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition measurement via controlled heating of crystalline sample in capillary tube; endpoint defined as temperature range of complete solid-to-liquid transition. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder dispersion using laser scattering principle to derive volume-based particle size distribution (D10, D50, D90). |
| pH of Aqueous Suspension | Potentiometric pH Measurement | Measurement of hydrogen ion activity in a defined suspension (e.g., 1% w/v in water) using calibrated glass electrode pH meter. |
| Microbial Limits | Membrane Filtration and Plate Count | Enumeration of aerobic mesophilic microorganisms and detection of specified pathogens (e.g., E. coli, S. aureus) following USP <61> and <62>. |
Technical Specifications of 3-N-FMOC-3-PHENYLPROPIONIC ACID
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (LC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 148–152°C |
| Identification (NMR) | Consistent with structure |
| Optical Rotation | +15.0 to +19.0° (c=1, DMF) |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 3-N-FMOC-3-PHENYLPROPIONIC ACID
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 3-N-FMOC-3-PHENYLPROPIONIC ACID
Safety Information of 3-N-FMOC-3-PHENYLPROPIONIC ACID
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 3-N-FMOC-3-PHENYLPROPIONIC ACID
Industrial 3-N-FMOC-3-PHENYLPROPIONIC ACID Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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