(R)-9-[2-(DIETHYLPHOSPHONOMETHOXY)PROPYL] ADENINE Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 180587-75-1 |
| Product name | (R)-9-[2-(DIETHYLPHOSPHONOMETHOXY)PROPYL] ADENINE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for (R)-9-[2-(DIETHYLPHOSPHONOMETHOXY)PROPYL] ADENINE
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk (R)-9-[2-(DIETHYLPHOSPHONOMETHOXY)PROPYL] ADENINE Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of (R)-9-[2-(DIETHYLPHOSPHONOMETHOXY)PROPYL] ADENINE
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Antiviral agents (e.g., nucleotide analog prodrugs for treating hepatitis B virus, HBV) | Chemical synthesis and biotransformation |
| Biotechnology | Molecular probe for studying viral replication mechanisms | Laboratory-scale synthesis and purification |
| Drug Development | Optimization of bioavailability and target specificity of nucleotide-based therapeutics | Structural modification and pharmacological screening |
Manufacturing Quality Control of (R)-9-[2-(DIETHYLPHOSPHONOMETHOXY)PROPYL] ADENINE
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the color, physical state, and presence of visible foreign matter under natural or standard lighting conditions. |
| Identification | Fourier Transform Infrared Spectroscopy (FT-IR) | Compare the sample spectrum with a reference spectrum to confirm consistency of characteristic functional group absorption peaks (e.g., P=O, N-H, C-O). |
| Nuclear Magnetic Resonance Spectroscopy (¹H-NMR, ³¹P-NMR) | Analyze structural features using proton and phosphorus NMR to confirm stereochemistry (R-configuration) and substituent positions. | |
| High-Performance Liquid Chromatography (HPLC) | Compare retention times with reference standards for qualitative identification. | |
| Assay | High-Performance Liquid Chromatography (HPLC) | Use a reversed-phase column (e.g., C18) and UV detector (~260 nm) for quantitative analysis of the active ingredient via external or internal standard methods. |
| Related Substances (Impurities) | HPLC with Gradient Elution | Detect process-related impurities and degradation products (e.g., dephosphorylated, oxidized, or isomeric compounds), typically requiring detection sensitivity down to 0.1%. |
| Chiral Purity | Chiral High-Performance Liquid Chromatography (Chiral HPLC) | Use chiral stationary phase columns to separate (R) and (S) enantiomers; evaluate enantiomeric excess (ee value) to ensure stereoselectivity. |
| Water Content | Karl Fischer Titration | Determine water content (crystalline or adsorbed water) using volumetric or coulometric methods; suitable for trace moisture analysis. |
| Residual Solvents | Gas Chromatography (GC) | Detect residual organic solvents (e.g., methanol, ethanol, dichloromethane, acetonitrile) from manufacturing processes in accordance with ICH Q3C guidelines. |
| Sulfated Ash | Sulfated Ash Test | Weigh residue after high-temperature ashing to determine total inorganic impurities; acceptance limit typically ≤0.1%. |
| Heavy Metals | Heavy Metals Test (Sulfide Colorimetry or ICP-MS) | Traditional method uses sulfide precipitation and color comparison (e.g., lead sulfide); modern approaches employ Inductively Coupled Plasma Mass Spectrometry (ICP-MS) to detect elemental impurities such as lead, cadmium, and mercury. |
| Crystal Form Analysis | X-Ray Powder Diffraction (XRPD) | Identify different crystalline forms or amorphous states to ensure batch-to-batch consistency in physical stability and solubility. |
| Particle Size Distribution | Laser Diffraction Analysis (LDA) | Evaluate particle size distribution for solid active pharmaceutical ingredients, impacting dissolution rate and formulation performance. |
| pH Value (Solution) | pH Meter Measurement | Prepare an aqueous solution at specified concentration and measure acidity/alkalinity using a calibrated pH meter. |
| Microbial Limits | Microbial Limits Testing | Perform tests per pharmacopoeial requirements for total aerobic microbial count, total yeast and mold count, and specified control organisms (e.g., Escherichia coli) to ensure microbiological safety. |
Technical Specifications of (R)-9-[2-(DIETHYLPHOSPHONOMETHOXY)PROPYL] ADENINE
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 178°C - 182°C |
| Optical Rotation | +15.0° to +17.0° (c=1, in methanol) |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of (R)-9-[2-(DIETHYLPHOSPHONOMETHOXY)PROPYL] ADENINE
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
Packaging of (R)-9-[2-(DIETHYLPHOSPHONOMETHOXY)PROPYL] ADENINE
Industrial (R)-9-[2-(DIETHYLPHOSPHONOMETHOXY)PROPYL] ADENINE Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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