China Factory Direct
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| CAS number | 18063-03-1 |
| Product name | 2,6-Difluorobenzamide |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pesticides | Fungicide | Used as an active ingredient to control fungal diseases on multiple crops |
| Pharmaceuticals | Intermediate | Used in the synthesis of certain pharmaceuticals or biologically active compounds |
| Research | Laboratory research | Applied in chemical reactions and biological studies in laboratory settings |
| Materials science | New material synthesis | Serves as a raw material for synthesizing novel polymeric materials or other chemicals |
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Appearance and Physical Properties | Visual Inspection, Melting Point Determination | Observe the color, crystalline form, and physical state of the sample; use a melting point apparatus to determine the melting range (typical melting point range: 115–120°C), to assess purity and the presence of impurities. |
| Determination of Content (Main Component) | HPLC (High-Performance Liquid Chromatography) | Use a C18 column with methanol/water or acetonitrile/water as the mobile phase, detect using a UV detector (wavelength 220–254 nm), and calculate the content of 2,6-difluorobenzamide using external or internal standard methods, ensuring high accuracy and good reproducibility. |
| Moisture Content | Karl Fischer Titration | Utilize an iodine-sulfur dioxide-pyridine-methanol system for quantitative reaction with water, and determine moisture content by electrochemical or visual endpoint detection, suitable for trace moisture analysis (typically ≤0.5%). |
| Solvent Residue | Gas Chromatography (GC) | Use headspace or direct injection, separate common organic solvents (e.g., methanol, ethanol, dichloromethane, acetonitrile) using a capillary column, and quantify using FID detector, in compliance with ICH Q3C guidelines on residual solvents. |
| Impurity Profile Analysis | HPLC-UV / HPLC-MS | Separate potential impurities (e.g., unreacted raw material 2,6-difluorobenzoic acid, de-fluorinated products, dimerization products) using gradient elution HPLC, and identify structures using mass spectrometry (MS), controlling single impurities and total impurities below specified limits (e.g., <0.1%). |
| Inorganic Impurities (e.g., Chlorides, Sulfates) | Ion Chromatography (IC) or Colorimetric Method | Ion chromatography can precisely determine anions such as Cl⁻ and SO₄²⁻; colorimetric methods (e.g., silver nitrate for chlorides) are suitable for rapid screening, ensuring compliance with pharmacopoeia requirements for inorganic impurities. |
| Melting Point | Capillary Melting Point Apparatus | Determine the melting point range using standard methods, for identification and preliminary purity assessment, comparing with literature values (approximately 115–120°C) to judge whether it meets specifications. |
| Crystalline Form Analysis (Optional) | X-ray Powder Diffraction (XRPD) | Used to confirm crystalline form, avoiding polymorphic effects on solubility and stability, applicable for quality control of high-purity APIs or raw materials for formulations. |
| UV Absorption Spectral Characteristics | UV-Visible Spectrophotometry (UV-Vis) | Determine characteristic absorption peaks (typically strong absorption around 225–235 nm) in ethanol or methanol, used for qualitative identification and rapid estimation of concentration, assisting in method validation with HPLC. |
| Heavy Metal Residues | Atomic Absorption Spectroscopy (AAS) or ICP-MS | Determine the content of heavy metals such as lead, cadmium, mercury, and arsenic according to pharmacopoeial methods (e.g., USP <231> or ICH Q3D), ensuring they are below safe limits (in parts per million, ppm). |
| Test Item | Specification |
|---|---|
| Appearance | White to almost white crystalline powder |
| Purity | >=98.5% (HPLC) |
| Melting Point | 142.0 - 146.0 °C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.