METHYL 2-[(S)-3-{(E)-3-[2-(7-CHLORO-2-QUINOLYL)VINYL]PHENYL}-3-HYDROXYPROPYL]BENZOATE Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 181139-72-0 |
| Product name | METHYL 2-[(S)-3-{(E)-3-[2-(7-CHLORO-2-QUINOLYL)VINYL]PHENYL}-3-HYDROXYPROPYL]BENZOATE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 181139-72-0
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 181139-72-0 Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 181139-72-0
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Industry | Intermediate | Used in the synthesis of biologically active compounds, particularly as a potential precursor or intermediate in anticancer drug research. |
| Medical Research | Research Tool | Applied in laboratory studies to investigate its mechanism of action at the cellular level and assess its therapeutic potential. |
| Biotechnology | Molecular Biology Research | Employed as a molecular probe or label to elucidate interactions in specific biological processes. |
Manufacturing Quality Control of 181139-72-0
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification using reverse-phase HPLC with UV detection at ~254 nm, comparing peak area against a certified reference standard. |
| Related Substances (Impurities) | HPLC-UV/DAD | Separation and detection of structurally related impurities using gradient HPLC with diode-array detection and peak purity assessment. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection, quantifying residual solvents (e.g., methanol, toluene, DMF) per ICH Q3C guidelines. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration measuring water via iodine generation and stoichiometric reaction with sample moisture. |
| Heavy Metals (Total) | ICP-MS | Quantification of elemental impurities (e.g., Pb, Cd, Ni, As) after acid digestion, per ICH Q3D requirements. |
| Chloride Content | Ion Chromatography (IC) | Separation and conductivity detection of chloride ions in aqueous extract, calibrated against chloride standards. |
| Optical Rotation | [α]D Measurement | Determination of specific optical rotation using a polarimeter at 20 °C and sodium D-line (589 nm) to confirm chiral integrity. |
| Residue on Ignition | Gravimetric Analysis | Measurement of inorganic ash content after high-temperature incineration (700–800 °C) and weighing of residual residue. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry or wet dispersed sample to determine D10, D50, D90 values based on light scattering principles. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid-to-liquid phase transition occurs, using calibrated digital melting point instrument. |
| pH of Aqueous Suspension | pH Meter | Measurement of pH in a defined suspension (e.g., 1% w/v in water) using calibrated pH electrode. |
| Microbial Contamination | Membrane Filtration & Plate Count | Enumeration of aerobic microorganisms and absence testing for specified pathogens per USP <61> and <62>. |
Technical Specifications of 181139-72-0
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Melting Point | 142–146°C |
| Water Content (KF) | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 181139-72-0
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| Lot/Batch Number | *Required fields | |
Packaging of 181139-72-0
Industrial 181139-72-0 Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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