2-Chloro-4-(trifluoromethyl)benzonitrile Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 1813-33-8 |
| Product name | 2-Chloro-4-(trifluoromethyl)benzonitrile |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2-Chloro-4-(trifluoromethyl)benzonitrile
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2-Chloro-4-(trifluoromethyl)benzonitrile Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2-Chloro-4-(trifluoromethyl)benzonitrile
| Industry | Application | Process |
|---|---|---|
| Pesticides | Key intermediate in the synthesis of the insecticide flupyradifurone | Used to prepare flupyradifurone via multi-step reactions including nitration, reduction, diazotization, cyanation, and chlorination/fluorination |
| Pharmaceuticals | Used to synthesize candidate drug molecules containing a trifluoromethylbenzonitrile moiety with antitumor and anti-inflammatory activity | Serves as a structural building block in coupling reactions (e.g., Suzuki, Heck) or functional group transformations to construct targeted small-molecule inhibitor scaffolds |
| Materials Science | Building block for high-performance liquid crystal monomers and organic light-emitting diode (OLED) materials | After derivatization (e.g., borylation or halogen exchange), participates in cross-coupling reactions to introduce synergistic electron-withdrawing trifluoromethyl and cyano groups, enabling precise tuning of molecular energy levels and mesogenic properties |
Manufacturing Quality Control of 2-Chloro-4-(trifluoromethyl)benzonitrile
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | Gas Chromatography (GC) with FID detection | Quantitative determination based on peak area comparison against a certified reference standard under optimized chromatographic conditions. |
| Water Content | Karl Fischer Titration | Electrochemical titration measuring water via iodine-sulfur dioxide reaction in anhydrous methanol-based solvent. |
| Residual Solvents | Gas Chromatography (GC) with Headspace sampling | Separation and quantification of volatile organic solvents using headspace equilibrium and flame ionization detection. |
| Heavy Metals | Inductively Coupled Plasma Optical Emission Spectrometry (ICP-OES) | Multi-element quantitative analysis based on atomic emission intensities from plasma-excited sample aerosol. |
| Chloride Impurity | Ion Chromatography (IC) | Separation and quantification of chloride ions using anion-exchange column and conductivity detection. |
| Acid Value | Acid-Base Titration with NaOH | Neutralization of acidic impurities using standardized sodium hydroxide solution and potentiometric endpoint detection. |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity against specified criteria under controlled lighting conditions. |
| Melting Point | Capillary Melting Point Apparatus | Determination of solid-to-liquid transition temperature using calibrated capillary tube method per USP <741>. |
| Residue on Ignition | Gravimetric Analysis | Measurement of non-volatile inorganic residue after high-temperature ashing at 600-800 C. |
| Organic Volatile Impurities (e.g., chlorobenzene, dichloromethane) | Gas Chromatography (GC) with FID | Identification and quantification of specified volatile impurities using retention time matching and external calibration. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light induced by chiral impurities or enantiomeric excess. |
| Particle Size Distribution | Laser Diffraction | Analysis of particle size distribution in dispersed solid sample based on angular scattering pattern of laser beam. |
Technical Specifications of 2-Chloro-4-(trifluoromethyl)benzonitrile
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 68–72°C |
| Identification (NMR) | Conforms to reference spectrum |
| Identification (IR) | Conforms to reference spectrum |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2-Chloro-4-(trifluoromethyl)benzonitrile
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2-Chloro-4-(trifluoromethyl)benzonitrile
Safety Information of 2-Chloro-4-(trifluoromethyl)benzonitrile
| Pictograms |  |
| Signal Word | Danger |
| Safety Data Sheet | |
Packaging of 2-Chloro-4-(trifluoromethyl)benzonitrile
Industrial 2-Chloro-4-(trifluoromethyl)benzonitrile Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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