tert-Butyl 4-aminobenzoate Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 18144-47-3 |
| Product name | tert-Butyl 4-aminobenzoate |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Material GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for tert-Butyl 4-aminobenzoate
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk tert-Butyl 4-aminobenzoate Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of tert-Butyl 4-aminobenzoate
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Used in the synthesis of local anesthetics (e.g., benzocaine derivatives) and antitumor agents (e.g., folate antagonists) | Deprotected or coupled under acid catalysis in inert solvents to yield 4-aminobenzoic acid or its active amide/ester derivatives |
| Organic Synthesis | Employed as an amino protecting group in multistep syntheses to suppress unwanted side reactions at the amino group | Introduced via tert-butoxycarbonyl (Boc) protection under basic or mildly acidic conditions, followed by selective deprotection with trifluoroacetic acid (TFA) or HCl/dioxane |
| Materials Science | Utilized as a building block for liquid crystal monomers or functional polymers | Integrated into conjugated backbones via diazotization-coupling, acid chloride formation, or palladium-catalyzed cross-coupling (e.g., Suzuki, Heck reactions) to tailor mesomorphic behavior and optoelectronic properties |
Manufacturing Quality Control of tert-Butyl 4-aminobenzoate
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 254 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification based on retention time matching and threshold limits per ICH Q3B. |
| Residual Solvents | GC-FID | Detection and quantification of volatile organic solvents (e.g., THF, toluene, methanol) using gas chromatography with flame ionization detection against calibrated standards. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine trace water content based on stoichiometric reaction with water. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (e.g., Pb, Cd, As, Hg) after acid digestion, using inductively coupled plasma mass spectrometry for sub-ppb sensitivity. |
| Residual Palladium | ICP-OES | Quantification of palladium residues (e.g., from catalytic hydrogenation) after microwave-assisted digestion, using inductively coupled plasma optical emission spectroscopy. |
| Melting Point | Capillary Melting Point Apparatus | Determination of solid-to-liquid transition temperature range using controlled heating and visual observation of sample collapse in a capillary tube. |
| Appearance | Visual Inspection | Assessment of physical state, color, and homogeneity against established reference standards under controlled lighting and viewing conditions. |
| Chloride Content | Ion Chromatography | Separation and quantification of chloride ions using anion-exchange column with suppressed conductivity detection after aqueous extraction. |
| Loss on Drying | Gravimetric Method | Measurement of weight loss after drying under specified temperature and vacuum conditions to determine volatile and moisture content. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light induced by chiral molecules in solution, using sodium D-line at specified concentration and path length. |
| Particle Size Distribution | Laser Diffraction | Analysis of particle size via scattering pattern of laser beam passed through dispersed sample, converted to volume-based distribution using Mie theory. |
Technical Specifications of tert-Butyl 4-aminobenzoate
| Test Item | Specification |
|---|---|
| Appearance | Off-white crystalline solid |
| Purity | >=98.0% (by LC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 108–112°C |
| Identification (NMR) | Conforms to reference spectrum |
| Identification (IR) | Conforms to reference spectrum |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of tert-Butyl 4-aminobenzoate
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of tert-Butyl 4-aminobenzoate
Packaging of tert-Butyl 4-aminobenzoate
Industrial tert-Butyl 4-aminobenzoate Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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