China Factory Direct
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| CAS number | 18173-64-3 |
| Product name | TERT-BUTYLDIMETHYLSILANOL |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty GradeReagent Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Organic Synthesis | Used as a precursor for silyl protecting groups to protect functional groups such as hydroxyl and amino groups | Reacts with alcohols or amines under acidic or basic conditions to form corresponding tert-butyldimethylsilyl ethers or silylamines, enhancing selectivity in subsequent reactions |
| Medicinal Chemistry | Applied in functional group protection of pharmaceutical intermediates to improve synthetic efficiency and yield | Undergoes silylation with reactive functional groups (e.g., –OH, –NH₂); the protecting group is subsequently removed after completion of the target reaction to regenerate the original functional group |
| Materials Science | Employed as a surface modifier to enhance material hydrophobicity or interfacial compatibility | Forms Si–O–M bonds with inorganic surfaces (e.g., glass, metal oxides) via its silanol group, enabling surface functionalization |
| Analytical Chemistry | Used as a derivatization reagent to improve volatility and detection sensitivity of polar compounds in GC or LC analysis | Reacts with polar functional groups in samples (e.g., –COOH, –OH) to generate volatile silyl derivatives, facilitating chromatographic separation and detection |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | Gas Chromatography (GC) with FID detection | Quantifies main component by retention time and peak area comparison against certified reference standard. |
| Residual Solvents | Headspace Gas Chromatography (HS-GC) | Volatile impurities are vaporized in sealed vials and separated/quantified by GC. |
| Water Content | Karl Fischer Titration | Electrochemical titration using iodine-sulfur dioxide reaction to determine trace water content. |
| Acidity (as HCl) | Acid-Base Titration with NaOH | Neutralization of acidic impurities using standardized sodium hydroxide solution and potentiometric endpoint detection. |
| Chloride Content | Ion Chromatography (IC) | Separation and quantification of chloride anions based on ion exchange and conductivity detection. |
| Heavy Metals (Pb, Cd, Hg, As) | ICP-MS | Multi-element detection via plasma ionization and mass spectrometric quantification at sub-ppq levels. |
| Residue on Ignition | Gravimetric Analysis | Measures non-volatile inorganic residue after high-temperature ashing and weighing. |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity against established reference standards under controlled lighting. |
| Density | Digital Density Meter | Measures mass per unit volume using oscillating U-tube principle at specified temperature. |
| Refractive Index | Refractometry | Determines light bending angle in sample at 20 C using calibrated refractometer. |
| Boiling Point | Distillation Apparatus (Micro Method) | Identifies temperature range at which compound distills under reduced pressure (e.g., 10 mmHg). |
| Specific Optical Rotation | Polarimetry | Measures rotation of plane-polarized light caused by chiral impurities or enantiomeric excess. |
| Test Item | Specification |
|---|---|
| Appearance | Colorless liquid |
| Purity | >=98.0% (GC) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Refractive Index (n20/D) | 1.415–1.425 |
| Relative Density (20°C/25°C) | 0.825–0.835 g/cm³ |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.