4-Methyl-1,2,3-thiadiazole-5-carboxylic acid Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 18212-21-0 |
| Product name | 4-Methyl-1,2,3-thiadiazole-5-carboxylic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeReagent Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4-Methyl-1,2,3-thiadiazole-5-carboxylic acid
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4-Methyl-1,2,3-thiadiazole-5-carboxylic acid Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4-Methyl-1,2,3-thiadiazole-5-carboxylic acid
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used as a pharmaceutical intermediate in the synthesis of biologically active thiodiazole compounds, including anti-inflammatory, antimicrobial, and antitumor drug candidates | Introduced into target molecular structures via amidation, esterification, or coupling reactions |
| Pesticides | Used as a pesticide intermediate in the synthesis of novel insecticides or herbicides | Employed in nucleophilic substitution or cyclization reactions to construct active molecular scaffolds |
| Chemical Research | Used as an organic building block for constructing functional molecules containing thiodiazole heterocycles | Serves as a carboxylic acid functional group precursor in multicomponent reactions or metal-catalyzed couplings |
Manufacturing Quality Control of 4-Methyl-1,2,3-thiadiazole-5-carboxylic acid
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at ~220–254 nm, based on peak area comparison against a certified reference standard. |
| Related Substances | HPLC-UV/DAD | Separation and identification of impurities (e.g., starting materials, intermediates, degradation products) via gradient HPLC with diode-array detection and spectral library matching. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection for quantification of common solvents (e.g., methanol, acetone, ethyl acetate) per ICH Q3C guidelines. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic elements (Pb, Cd, As, Hg, Ni) after acid digestion, offering sub-pptr detection limits compliant with ICH Q3D. |
| Chloride Content | Ion Chromatography (IC) | Separation and quantification of chloride ions using anion-exchange column and suppressed conductivity detection. |
| Moisture Content | Karl Fischer Titration (Coulometric) | Electrochemical titration based on the reaction of iodine with water in anhydrous methanol/pyridine medium; suitable for low-moisture solids (<1%). |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition determination by observing solid-to-liquid phase change under controlled heating rate (e.g., 1–2 °C/min). |
| Residue on Ignition (Sulfated Ash) | Gravimetric Analysis | Quantification of inorganic residue after high-temperature (700–800 °C) incineration of sample with sulfuric acid pretreatment. |
| pH of Aqueous Suspension | Potentiometric pH Measurement | Measurement of hydrogen ion activity in a defined suspension (e.g., 1% w/v in water) using calibrated pH electrode. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry or wet dispersed sample via light scattering pattern to determine D10, D50, D90 values per ISO 13320. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light passing through a solution, indicating chiral purity (if applicable; compound is achiral but method included for identity verification per pharmacopeial monographs). |
Technical Specifications of 4-Methyl-1,2,3-thiadiazole-5-carboxylic acid
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% (HPLC) |
| Melting Point | 162–166 °C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4-Methyl-1,2,3-thiadiazole-5-carboxylic acid
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4-Methyl-1,2,3-thiadiazole-5-carboxylic acid
Safety Information of 4-Methyl-1,2,3-thiadiazole-5-carboxylic acid
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 4-Methyl-1,2,3-thiadiazole-5-carboxylic acid
Industrial 4-Methyl-1,2,3-thiadiazole-5-carboxylic acid Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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