3-Chloro-4-hydroxyphenylboronic acid Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 182344-13-4 |
| Product name | 3-Chloro-4-hydroxyphenylboronic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 3-Chloro-4-hydroxyphenylboronic acid
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 3-Chloro-4-hydroxyphenylboronic acid Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 3-Chloro-4-hydroxyphenylboronic acid
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate for synthesizing active pharmaceutical ingredients (APIs), such as antitumor agents and kinase inhibitors | Used in Suzuki-Miyaura coupling to construct aryl–aryl bonds |
| Agrochemicals | Intermediate for synthesizing bioactive pesticide molecules, such as herbicides or fungicides | Applied in palladium-catalyzed cross-coupling to introduce chlorohydroxyphenyl moieties |
| Organic Synthesis | Multifunctional arylboronic acid reagent for constructing complex aromatic compounds | Employed in Suzuki coupling with aryl halides under basic conditions |
| Materials Science | Precursor for organic functional materials with optoelectronic properties (e.g., OLED materials) | Used in transition-metal-catalyzed C–C bond formation to prepare conjugated molecular frameworks |
Manufacturing Quality Control of 3-Chloro-4-hydroxyphenylboronic acid
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by comparison of peak area against a certified reference standard using reversed-phase chromatography and UV detection at ~254 nm. |
| Related Substances (Impurities) | HPLC-UV or UPLC-UV | Separation and quantification of structurally related impurities (e.g., 3-chloro-4-methoxybenzeneboronic acid, residual starting materials) using gradient elution and UV detection. |
| Residual Solvents (e.g., THF, MeOH, EtOAc) | GC-FID | Headspace gas chromatography with flame ionization detection to quantify volatile organic solvents per ICH Q3C guidelines. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration based on the reaction of iodine with water in anhydrous methanol/pyridine medium; suitable for low-level moisture determination. |
| Inorganic Residues (Sulfated Ash) | Gravimetric Analysis | Ignition of sample at 600–700 °C followed by weighing of non-volatile inorganic residue after sulfuric acid treatment. |
| Heavy Metals (Pb, Cd, Hg, As) | ICP-MS | Multi-element quantification via plasma ionization and mass spectrometric detection at trace levels (ppq–ppt), compliant with ICH Q3D. |
| Chloride Ion Impurity | Ion Chromatography (IC) with Conductivity Detection | Separation of anions on anion-exchange column and quantitative detection of chloride based on electrical conductivity. |
| Residual Palladium (from synthesis catalyst) | ICP-MS or ICP-OES | Direct quantification of Pd after microwave-assisted acid digestion; ICP-MS preferred for sub-ppb sensitivity. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition measurement by observing solid-to-liquid phase change under controlled heating rate (e.g., 1–2 °C/min). |
Technical Specifications of 3-Chloro-4-hydroxyphenylboronic acid
| Test Item | Specification |
|---|---|
| Appearance | Off-white crystalline solid |
| Purity | >=98.5% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 182–186°C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 3-Chloro-4-hydroxyphenylboronic acid
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 3-Chloro-4-hydroxyphenylboronic acid
Safety Information of 3-Chloro-4-hydroxyphenylboronic acid
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 3-Chloro-4-hydroxyphenylboronic acid
Industrial 3-Chloro-4-hydroxyphenylboronic acid Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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