N-(TERT-BUTOXYCARBONYL)-P-TOLUENESULFONAMIDE Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 18303-04-3 |
| Product name | N-(TERT-BUTOXYCARBONYL)-P-TOLUENESULFONAMIDE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for N-(TERT-BUTOXYCARBONYL)-P-TOLUENESULFONAMIDE
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk N-(TERT-BUTOXYCARBONYL)-P-TOLUENESULFONAMIDE Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of N-(TERT-BUTOXYCARBONYL)-P-TOLUENESULFONAMIDE
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used as an amino-protecting reagent for selective protection of amino groups in peptide and drug molecule synthesis | In organic synthesis, reacts with amines to form stable Boc-protected amines; deprotection is achieved under acidic conditions to enable subsequent functional group transformations or coupling reactions |
| Agrochemicals | Used as an intermediate in the synthesis of nitrogen-containing heterocyclic agrochemicals | Participates in constructing biologically active agrochemical molecules containing sulfonamide moieties, providing tunable reaction sites |
| Fine Chemicals | Used as an organic building block for preparing functionalized sulfonamide derivatives | Introduces p-toluenesulfonyl or tert-butoxycarbonyl functional groups via nucleophilic substitution, coupling, or deprotection reactions for material or ligand design |
Manufacturing Quality Control of N-(TERT-BUTOXYCARBONYL)-P-TOLUENESULFONAMIDE
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at ~210–230 nm, comparing peak area against a certified reference standard. |
| Identity | FT-IR Spectroscopy | Confirmation via characteristic absorption bands (e.g., C=O stretch at ~1700 cm⁻¹, S=O stretches at ~1350 and ~1170 cm⁻¹, N–H stretch if present). |
| Residual Solvents | GC-FID | Separation and quantification of volatile organic solvents (e.g., THF, DCM, toluene) using capillary GC with flame ionization detection. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration measuring water via iodine generation and stoichiometric reaction with water in anhydrous methanol-based reagent. |
| Heavy Metals (Pb, Cd, Hg, As) | ICP-MS | Multi-element quantification after acid digestion, based on elemental mass-to-charge ratio detection with high sensitivity and low detection limits. |
| Residual Tosyl Chloride | GC-MS | Detection and quantification of unreacted tosyl chloride impurity by gas chromatography coupled with mass spectrometric identification. |
| Related Substances | HPLC-UV (with gradient elution) | Separation and quantification of structurally related impurities (e.g., Boc-amine, des-Boc species, sulfonyl hydrolysis products) using optimized reversed-phase conditions. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition measurement via controlled heating; sharp melting range confirms crystalline purity and identity. |
| Residue on Ignition | Gravimetric Analysis (Weight Loss on Ignition) | Determination of inorganic ash content after high-temperature incineration (500–600 °C) and weighing of residual residue. |
| Chloride Ion Impurity | Ion Chromatography (IC) with Conductivity Detection | Separation of anions on anion-exchange column and quantitative detection of chloride via conductivity response relative to calibration standards. |
Technical Specifications of N-(TERT-BUTOXYCARBONYL)-P-TOLUENESULFONAMIDE
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% (LC-MS) |
| Water Content (KF) | <=0.5% |
| Melting Point | 128–132°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of N-(TERT-BUTOXYCARBONYL)-P-TOLUENESULFONAMIDE
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of N-(TERT-BUTOXYCARBONYL)-P-TOLUENESULFONAMIDE
Safety Information of N-(TERT-BUTOXYCARBONYL)-P-TOLUENESULFONAMIDE
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of N-(TERT-BUTOXYCARBONYL)-P-TOLUENESULFONAMIDE
Industrial N-(TERT-BUTOXYCARBONYL)-P-TOLUENESULFONAMIDE Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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