4,5-DIFLUORO-2-METHYLBENZOIC ACID Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 183237-86-7 |
| Product name | 4,5-DIFLUORO-2-METHYLBENZOIC ACID |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4,5-DIFLUORO-2-METHYLBENZOIC ACID
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4,5-DIFLUORO-2-METHYLBENZOIC ACID Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4,5-DIFLUORO-2-METHYLBENZOIC ACID
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Chemicals | Pharmaceutical Intermediates | Serves as a key structural unit in the synthesis of novel antidiabetic active pharmaceutical ingredients (APIs), such as dipeptidyl peptidase-4 (DPP-4) inhibitors, and their active components. |
| Agrochemicals | Agrochemical Intermediates | Used in the synthesis of fluorinated benzoylurea- or amide-based insecticides and herbicides, leveraging fluorine atoms to enhance biological activity and metabolic stability. |
| Organic Synthesis | Fluoroaromatic Building Blocks | Enables construction of fluorinated aromatic derivatives via functional group transformations—including acylation, amidation, esterification, or coupling reactions—for drug discovery screening or material modification. |
Manufacturing Quality Control of 4,5-DIFLUORO-2-METHYLBENZOIC ACID
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at ~230 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV or UPLC-MS | Separation and quantification of structurally related impurities (e.g., isomers, dehalogenated, or hydrolyzed by-products) using gradient elution and UV or mass-selective detection. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify volatile organic solvents (e.g., methanol, acetone, ethyl acetate) based on retention time and calibration curves. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (e.g., Pb, Cd, Hg, As) after acid digestion, leveraging high sensitivity and isotopic resolution. |
| Chloride Impurity | Ion Chromatography (IC) | Separation and conductivity detection of chloride ions in aqueous extract; detects residual HCl or chloride salts from synthesis. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration using iodine generated in situ to quantify trace water content based on stoichiometric reaction with Karl Fischer reagent. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition measurement via controlled heating; used for identity confirmation and assessment of crystallinity/purity. |
| Appearance & Color | Visual Inspection / Hazen Color Scale | Subjective evaluation of physical state (white to off-white crystalline solid) and color intensity against platinum-cobalt standards. |
| Residue on Ignition | Gravimetric Analysis (Weight Loss on Ignition) | Determination of inorganic ash content after high-temperature incineration (700–800 °C) and weighing of residual residue. |
| Optical Rotation | Polarimetry | Measurement of specific rotation using sodium D-line light to confirm chiral purity (if applicable); though compound is achiral, used to detect chiral contaminants. |
Technical Specifications of 4,5-DIFLUORO-2-METHYLBENZOIC ACID
| Test Item | Specification |
|---|---|
| Appearance | Off-white crystalline solid |
| Purity | >=98.0% (by LC-MS) |
| Melting Point | 142–146°C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4,5-DIFLUORO-2-METHYLBENZOIC ACID
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4,5-DIFLUORO-2-METHYLBENZOIC ACID
Safety Information of 4,5-DIFLUORO-2-METHYLBENZOIC ACID
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 4,5-DIFLUORO-2-METHYLBENZOIC ACID
Industrial 4,5-DIFLUORO-2-METHYLBENZOIC ACID Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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