China Factory Direct
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| CAS number | 18344-51-9 |
| Product name | 2-Amino-3-methyl-5-nitropyridine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate in the synthesis of antitumor agents (e.g., gefitinib analogues) | Constructing heterocyclic frameworks via nucleophilic substitution, reduction, or coupling reactions |
| Agrochemicals | Precursor to active ingredients in novel insecticides or herbicides | Nitro group reduction, amine protection, and subsequent functional group transformations |
| Dyes | Structural unit in azo dyes or fluorescent dyes | Participating in diazotization-coupling reactions or metal coordination-based coloration processes |
| Materials Science | Preparation of nitrogen-containing functional materials (e.g., ligands, optoelectronic materials) | Introducing pyridine ring structures via coordination chemistry or polymerization reactions |
| Detection Item | Common Testing Methods | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the sample's color, physical form (e.g., pale yellow to brown-yellow crystalline powder), presence of foreign matter, or caking. |
| Purity | High-Performance Liquid Chromatography (HPLC) | Use reversed-phase chromatographic column with appropriate mobile phase (e.g., methanol/water or acetonitrile/buffer salt system) for separation, and UV detector for quantitative determination of the main peak purity. |
| Content Determination | HPLC External Standard Method / Titration Method | HPLC method: Calculate content by comparing peak areas with a reference standard; Titration method: Suitable for compounds containing amino groups, using acid-base titration or non-aqueous titration. |
| Related Substances (Impurities) | HPLC Gradient Elution Method | Separate the active ingredient from potential impurities (such as unreacted raw materials, by-products, degradation products) through gradient elution program; quantify using area normalization or correction factor methods. |
| Loss on Drying | Drying Method (105°C, constant weight) | Weigh the sample into a dried and constant-weight weighing bottle, dry at 105°C until constant weight in an oven, then calculate the percentage of weight loss. |
| Melting Point | Determination by Capillary Melting Point Apparatus | Measure initial and final melting temperatures using a digital melting point apparatus to assess crystalline purity and consistency. |
| Residual Solvents | Gas Chromatography (GC) | Use headspace injection or direct injection with polar or non-polar capillary columns, and FID or ECD detectors; quantify residual organic solvents by comparison with reference standards. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or ICP-MS | After sample digestion, determine levels of lead, cadmium, mercury, arsenic, etc., ensuring compliance with pharmacopoeial or ICH Q3D limits. |
| pH (Solution) | pH Meter Measurement | Dissolve the sample in water to a specified concentration (e.g., 1%), then measure pH using a calibrated pH meter. |
| Water Content | Karl Fischer Titration (Volumetric or Coulometric Method) | Determine trace moisture content using a KF titrator, especially suitable for thermally unstable or non-drying samples. |
| Test Item | Specification |
|---|---|
| Appearance | Yellow-brown solid |
| Purity | >=98.0% (LC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 128–132°C |
| Identification (NMR) | Conforms to reference spectrum |
| Heavy Metals | <=20 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Danger |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.