China Factory Direct
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| CAS number | 18368-76-8 |
| Product name | 2-Chloro-3-picoline |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
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| Pesticides | Intermediate for synthesizing neonicotinoid insecticides such as imidacloprid and acetamiprid | Used as a starting material—2-chloro-3-methylpyridine—in nucleophilic substitution, condensation, or coupling reactions to prepare target insecticides |
| Pharmaceuticals | Intermediate for synthesizing antidepressants, antiviral agents, and other active pharmaceutical ingredients (APIs) containing a pyridine ring | Employed as a key intermediate in acylation, alkylation, or metal-catalyzed cross-coupling reactions |
| Dyes & Pigments | Intermediate for synthesizing specialty functional dyes and photosensitive materials | Applied to construct nitrogen-containing heterocyclic chromophores; the pyridyl group is introduced via coupling or cyclization reactions |
| Chemical Intermediates | Intermediate for synthesizing other chloropyridine derivatives and functionalized heterocyclic compounds | Converted into various derivatives through hydrolysis, aminolysis, Grignard reactions, or catalytic hydrogenation |
| Detection Item | Common Analytical Method | Method Overview |
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| Assay (Purity) | Gas Chromatography (GC) with FID detector | Quantitative determination based on peak area comparison against a certified reference standard using a non-polar capillary column. |
| Related Substances | Gas Chromatography (GC) with FID or MS detection | Separation and quantification of impurities relative to the main peak using retention time and response factor calibration. |
| Residual Solvents | Headspace Gas Chromatography (HS-GC) | Volatile organic solvents are equilibrated in headspace vial and analyzed by GC-FID after thermal extraction. |
| Water Content | Karl Fischer Titration (Coulometric mode) | Electrochemical titration where iodine is generated in situ to react stoichiometrically with water in the sample. |
| Chloride Ion Impurity | Ion Chromatography (IC) with conductivity detection | Separation of anions on an ion-exchange column followed by quantitative detection via conductivity measurement. |
| Heavy Metals (as Pb) | Inductively Coupled Plasma Optical Emission Spectrometry (ICP-OES) | Atomization and excitation of metals in high-temperature plasma; emission intensity measured at characteristic wavelengths. |
| Acidity (as HCl) | Acid-Base Titration with NaOH standard solution | Neutralization of acidic impurities using standardized sodium hydroxide solution with potentiometric endpoint detection. |
| Color | Visual Comparison or Spectrophotometry (APHA/Pt-Co scale) | Measurement of yellowness index by comparing sample color to platinum-cobalt standard solutions or measuring absorbance at 430 nm. |
| Density | Digital Density Meter (Oscillating U-tube principle) | Determination of mass per unit volume based on resonant frequency shift of a vibrating U-shaped tube filled with sample. |
| Refractive Index | Refractometry (Abbe refractometer) | Measurement of light bending angle at air-sample interface to determine refractive index at specified temperature. |
| Non-Volatile Residue | Gravimetric Analysis (Evaporation and Weighing) | Sample evaporated to dryness under controlled conditions; residue weighed after cooling in desiccator. |
| Optical Rotation | Polarimetry | Measurement of angular rotation of plane-polarized light passing through a chiral sample solution at specified wavelength and temperature. |
| Test Item | Specification |
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| Appearance | Colorless to pale yellow liquid |
| Purity | >=98.0% (GC) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Refractive Index (n20/D) | 1.530–1.535 |
| Relative Density (20°C/25°C) | 1.120–1.130 g/cm³ |
| Odor | Characteristic pyridine-like odor |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.