China Factory Direct
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| CAS number | 183905-31-9 |
| Product name | AcetaMide, N-[(2S)-2-(acetyloxy)-3-chloropropyl]- |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Chemicals | Chiral building block for the synthesis of L-carnitine | Serves as a key chiral intermediate in constructing the structural backbone of L-carnitine via substitution and hydrolysis reactions, for the production of L-carnitine pharmaceuticals and nutritional supplements. |
| Pharmaceutical Chemicals | Chiral building block for the synthesis of (R)-4-amino-3-hydroxybutyric acid | Leverages its chiral center to prepare (R)-4-amino-3-hydroxybutyric acid through chemical transformations; this compound serves as a critical intermediate in synthesizing neuropharmaceuticals such as galantamine. |
| Pharmaceutical Chemicals | Chiral building block for the synthesis of (S)-3-chloro-2-hydroxypropyl derivatives | Acts as a versatile chiral source for preparing bioactive chiral alcohols, amines, and their derivatives via functional group transformations—such as acetyl hydrolysis and amination. |
| Organic Synthesis | Chiral reagent | Applied in asymmetric synthesis as a multifunctional chiral synthon bearing both a chlorine atom and an ester group, participating in nucleophilic substitution reactions to construct target chiral molecules. |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 210-220 nm, comparing peak area to a reference standard. |
| Chiral Purity (Enantiomeric Excess) | Chiral HPLC | Separation of (R)- and (S)-enantiomers on a chiral stationary phase, with UV detection and calculation of ee from peak area ratio. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common solvents (e.g., acetone, ethyl acetate, methanol) against calibrated standards. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine water content based on stoichiometric reaction with water. |
| Heavy Metals | ICP-OES | Multi-element quantification of Pb, Cd, Hg, As, and other regulated metals after acid digestion and plasma excitation emission measurement. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of chloride anion using suppressed conductivity detection after aqueous extraction. |
| Residual Acetic Acid | Acid-Base Titration | Direct titration with standardized NaOH solution using phenolphthalein indicator to determine free acetic acid content. |
| Melting Point | Capillary Melting Point Apparatus | Thermal analysis of solid sample in capillary tube; temperature range at which solid transitions to liquid is recorded. |
| Appearance | Visual Inspection | Assessment of physical state, color, and presence of visible particulates or discoloration under controlled white light. |
| Specific Optical Rotation | [alpha]D Measurement | Measurement of rotation angle of plane-polarized light at 589 nm to confirm chiral integrity and batch-to-batch consistency. |
| Related Substances | HPLC-UV | Detection and quantification of structurally related impurities (e.g., hydrolysis products, diastereomers) using gradient HPLC-UV. |
| Loss on Drying | Gravimetric Analysis | Weight loss measured after drying sample at specified temperature (e.g., 60 C, 2 h) under vacuum or nitrogen flow. |
| Test Item | Specification |
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| Appearance | White solid |
| Purity | >=98.0% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Optical Rotation | -11.0 to -9.0 deg (c=1, in chloroform) |
| Melting Point | 48 to 52 °C |
| Identification (NMR) | Consistent with structure |
| Identification (IR) | Consistent with structure |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.