Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 184177-81-9 |
| Product name | Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 184177-81-9
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 184177-81-9 Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 184177-81-9
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate for synthesizing selective histamine H3 receptor antagonists | Used as a key intermediate in multi-step organic synthesis to construct biologically active drug molecules |
| Biochemical Research | Research tool compound for histamine receptor functional studies | Applied in in vitro receptor binding assays and pharmacological evaluation to support mechanistic studies of neurotransmitter systems |
Manufacturing Quality Control of 184177-81-9
| Detection Item | Common Testing Methods | Method Overview |
|---|---|---|
| Identification Test | Infrared Spectroscopy (IR), High-Performance Liquid Chromatography (HPLC) | Confirm structural consistency by comparing the infrared absorption spectrum or retention time of the sample with that of the reference standard; HPLC is used to assess peak purity and retention behavior matching. |
| Content Determination | High-Performance Liquid Chromatography with Ultraviolet Detection (HPLC-UV) | Utilize reversed-phase chromatographic columns with UV detection (e.g., 254 nm or optimized wavelength) for quantitative analysis of the main component, using external standard or internal standard method. |
| Related Substances / Impurity Analysis | HPLC with Gradient Elution | Employ gradient elution to separate the main peak from potential impurities (such as synthetic intermediates or degradation products); impurity levels are calculated using area normalization or self-reference methods. |
| Loss on Drying | Drying Method (105°C to constant weight) | Dry the sample at 105°C until constant weight, calculate the percentage of mass loss to assess moisture and volatile substance content. |
| Residual Solvents | Gas Chromatography (GC-FID or GC-MS) | Follow ICH Q3C guidelines; use headspace or direct injection GC to detect organic solvents potentially remaining from synthesis (e.g., methanol, ethyl acetate, etc.). |
| Heavy Metals | Inductively Coupled Plasma Mass Spectrometry (ICP-MS) or Atomic Absorption Spectroscopy (AAS) | Detect element impurities such as lead, cadmium, arsenic, mercury, and copper according to pharmacopoeial general rules, ensuring compliance with safety limits (typically ≤10–20 ppm). |
| pH Value (if in solution formulation) | pH Meter Measurement | Prepare a solution at a defined concentration and measure its acidity or alkalinity using a calibrated pH meter to evaluate stability and suitability. |
| Melting Point | Capillary Melting Point Apparatus | Determine the melting temperature range of the compound as a physical constant to assist in identification and purity assessment. |
| Solubility | Visual Inspection or Turbidimetry | Observe dissolution behavior in different solvents (water, ethanol, DMSO, etc.) to provide reference data for formulation development. |
| Stability-Indicating Method | Forced Degradation Studies + HPLC Analysis | Subject samples to stress conditions (acid, base, oxidation, light, high temperature), then analyze degradation products using HPLC to verify whether the method can effectively detect potential degradation impurities. |
Technical Specifications of 184177-81-9
| Test Item | Specification |
|---|---|
| Appearance | Gray solid |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 148–152°C |
| Identification (NMR) | Consistent with structure |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 184177-81-9
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 184177-81-9
Packaging of 184177-81-9
Industrial 184177-81-9 Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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