China Factory Direct
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| CAS number | 18422-05-4 |
| Product name | Adenosine 5'-monophosphate monohydrate |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeFood Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used as a pharmaceutical intermediate in the synthesis of antiviral or cardiovascular drugs | Serves as a precursor molecule in chemical synthesis or enzyme-catalyzed reactions for constructing nucleotide derivatives |
| Biochemical Research | Used as a biochemical reagent to study nucleic acid metabolism, energy metabolism, and signal transduction mechanisms | Acts as a substrate or cofactor in in vitro enzymatic reaction systems for analysis of ATP-related metabolic pathways |
| Molecular Biology | Used in experimental buffer systems or as a stabilizer for PCR, DNA sequencing, and related applications | Formulated into reaction buffers to adjust ionic strength and pH, thereby maintaining enzymatic activity and nucleic acid stability |
| Food Industry (Nutritional Fortification) | Used as a food additive (e.g., flavor-enhancing nucleotides) to enhance taste | Applied synergistically with monosodium glutamate—either via Maillard reaction or direct addition—to intensify umami perception |
| Diagnostics Reagent Development | Used in clinical diagnostic kits, such as assays for energy metabolism–related enzyme activity | Employed as a reference standard or reaction substrate for quantitative detection via spectrophotometric or fluorometric methods |
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Assay (Main Component Analysis) | High-Performance Liquid Chromatography (HPLC) | Uses a reversed-phase C18 column with a mobile phase consisting of phosphate buffer and organic solvent (e.g., methanol), and detection by UV detector at 254 nm. Accurately determines the content of AMP monohydrate with good resolution and high reproducibility. |
| Purity Analysis | Liquid Chromatography-Mass Spectrometry (LC-MS) | Combines the separation capability of HPLC with the qualitative and quantitative advantages of mass spectrometry to confirm the main component and detect trace impurities (e.g., adenosine, phosphate), suitable for raw materials requiring high purity. |
| Impurity Testing (Related Substances) | HPLC (External Standard or Self-Dilution Method) | Separates potential process-related impurities (e.g., unreacted adenosine, di- or triphosphate derivatives) under specific chromatographic conditions; assesses impurity levels based on peak area ratios, compliant with ICH Q6A requirements. |
| Water Content Determination | Karl Fischer Titration | Specifically used to measure bound water content. As this compound is a monohydrate, this method accurately determines its crystalline water content, ensuring compliance with the "monohydrate" specification. |
| pH Test | pH Measurement (Potentiometric Method) | Dissolve an appropriate amount of sample in water and measure the solution pH using a pH meter. The pH should be controlled within a specified range (typically 5.0–7.0) to verify that its acid-base properties meet requirements. |
| Loss on Drying | Oven Drying Method (At Atmospheric Pressure) | The sample is dried at a specified temperature (e.g., 105°C) to constant weight, and the percentage weight loss is calculated to evaluate total moisture and volatile impurities. |
| Sulfated Ash (Residue on Ignition) | Ignition Method (High-Temperature Ashing) | The sample is ignited at high temperature (e.g., 600–800°C) to constant weight to determine the content of inorganic residue, assessing the presence of inorganic impurities such as metal ions. |
| Heavy Metals Test | Thioacetamide Method (Chinese Pharmacopoeia) | Detects heavy metals such as lead and cadmium by forming colored precipitates with thioacetamide, using colorimetry to ensure compliance with pharmaceutical standards. |
| UV-Visible Spectroscopy (UV-Vis) | UV Absorption Spectrophotometry | Measures absorbance at wavelengths between 254–260 nm for preliminary identification and supplementary assay purposes, confirming characteristic absorption peaks. |
| Infrared Spectroscopy (IR) | Fourier Transform Infrared Spectroscopy (FT-IR) | Confirms molecular structure through characteristic functional group absorption bands (e.g., phosphate groups, purine ring), verifying adenosine-5'-monophosphate monohydrate and ruling out isomers or impurities. |
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
| Optical Rotation | -20.0° to -24.0° (c=1, H2O) |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.