(S)-4-PHENYL-3-PROPIONYL-2-OXAZOLIDINONE Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 184363-66-4 |
| Product name | (S)-4-PHENYL-3-PROPIONYL-2-OXAZOLIDINONE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for (S)-4-PHENYL-3-PROPIONYL-2-OXAZOLIDINONE
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk (S)-4-PHENYL-3-PROPIONYL-2-OXAZOLIDINONE Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of (S)-4-PHENYL-3-PROPIONYL-2-OXAZOLIDINONE
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Chemistry | Chiral auxiliary for asymmetric synthesis of chiral drug intermediates | Used as an Evans-type chiral auxiliary in stereoselective acylation and alkylation reactions |
| Organic Synthesis | Construction of chiral centers for synthesizing optically pure compounds | Forms chiral acyl oxazolidinones with carboxylic acids, followed by enolization and electrophilic substitution |
| Drug Development | Key chiral building block for synthesizing antibiotics, antiviral agents, and cardiovascular drugs | Enables high enantioselectivity via auxiliary removal to recover target carboxylic acid derivatives |
Manufacturing Quality Control of (S)-4-PHENYL-3-PROPIONYL-2-OXAZOLIDINONE
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 210-230 nm, comparing peak area to a reference standard calibration curve. |
| Enantiomeric Excess (ee) | Chiral HPLC | Separation of (R)- and (S)-enantiomers on a chiral stationary phase, with quantification based on peak area ratio. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common organic solvents (e.g., acetone, ethyl acetate, toluene) against internal/external standards. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine trace water content via electrochemical endpoint detection. |
| Heavy Metals (as Pb) | ICP-MS | Multi-element quantification of heavy metals (Pb, Cd, Hg, As) after acid digestion, using inductively coupled plasma mass spectrometry for sub-ppb sensitivity. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of chloride ions using anion-exchange column with suppressed conductivity detection. |
| Residual Palladium | ICP-OES | Quantification of palladium catalyst residue after microwave-assisted acid digestion, using inductively coupled plasma optical emission spectroscopy. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition measurement by observing solid-to-liquid phase change under controlled heating rate (e.g., 1 C/min). |
| Specific Optical Rotation | [alpha]D Measurement | Determination of chiral compound rotation of plane-polarized light at 589 nm using a digital polarimeter, reported as degrees per (dm g/mL). |
| Loss on Drying (LOD) | Gravimetric Thermobalance | Mass loss measured after heating sample at 105 C under vacuum or nitrogen for fixed duration, expressed as weight percent. |
| Related Substances | HPLC-UV (Forced Degradation) | Detection and quantification of process-related impurities and degradation products using gradient HPLC-UV under stressed conditions (acid, base, oxidation, heat, light). |
| Particle Size Distribution | Laser Diffraction | Analysis of dry or wet dispersed sample using Mie scattering theory to determine volume-based particle size distribution (D10, D50, D90). |
Technical Specifications of (S)-4-PHENYL-3-PROPIONYL-2-OXAZOLIDINONE
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (LC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Melting Point | 78–82°C |
| Optical Rotation | +99.0 to +102.0° (c=1, in CHCl3) |
| Identification (NMR) | Conforms to reference spectrum |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of (S)-4-PHENYL-3-PROPIONYL-2-OXAZOLIDINONE
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of (S)-4-PHENYL-3-PROPIONYL-2-OXAZOLIDINONE
Safety Information of (S)-4-PHENYL-3-PROPIONYL-2-OXAZOLIDINONE
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of (S)-4-PHENYL-3-PROPIONYL-2-OXAZOLIDINONE
Industrial (S)-4-PHENYL-3-PROPIONYL-2-OXAZOLIDINONE Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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