China Factory Direct
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| CAS number | 1846-76-0 |
| Product name | ETHYL COUMARIN-3-CARBOXYLATE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Material GradeSpecialty GradeReagent GradeIndustrial GradeCosmetic GradeFood Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate for synthesizing anticoagulant and anticancer drugs | Reacted with coumarin-3-carboxylic acid via esterification to generate ethyl ester derivatives, serving as key precursors in drug synthesis |
| Organic Synthesis | Multifunctional organic synthesis intermediate for constructing complex molecular frameworks | Functional groups introduced via nucleophilic substitution, coupling reactions, etc., for peptide or heterocyclic compound synthesis |
| Fine Fragrances & Cosmetics | Fragrance ingredient imparting natural floral odor | Incorporated into perfumes and skincare products after microencapsulation or stabilization to enhance fragrance longevity |
| Materials Science | Synthesis of fluorescent and optoelectronic functional materials | Polymerized to produce polymeric materials with tailored fluorescence properties for use in sensors or LED devices |
| Analytical Chemistry | Fluorescent probe or reference standard for analytical detection | Employed as an internal standard or labeling reagent in liquid chromatography or mass spectrometry analyses, leveraging its strong fluorescence |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 310 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification based on retention time relative to reference standards or threshold limits. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify volatile organic solvents (e.g., ethanol, ethyl acetate) against calibration curves. |
| Heavy Metals | ICP-OES | Multi-element quantification of Pb, Cd, As, Hg, and Cr after acid digestion, based on atomic emission intensities at characteristic wavelengths. |
| Chloride Content | Potentiometric Titration | Titration with silver nitrate using a silver indicator electrode; endpoint detected by potential inflection due to AgCl precipitation. |
| Sulfated Ash | Gravimetric Analysis | Ignition of sample at 700-800 C after sulfuric acid treatment; residue mass measured as inorganic sulfate ash content. |
| Water Content | Karl Fischer Titration | Coulometric or volumetric titration measuring water via iodine-sulfur dioxide reaction in pyridine-methanol solvent system. |
| Melting Point | Capillary Melting Point Apparatus | Determination of solid-to-liquid phase transition temperature using calibrated capillary apparatus per USP <741>. |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity of solid material against established reference standards under controlled lighting. |
| Loss on Drying | Thermogravimetric Analysis (TGA) | Measurement of mass loss upon heating to 105 C for 2 hours, reflecting volatile content including residual moisture and low-boiling impurities. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light at 20 C using sodium D-line (589 nm) to assess chiral purity and identity. |
| pH of Aqueous Suspension | pH Meter | Determination of pH in a defined suspension (e.g., 1% w/v in water) using calibrated pH electrode per EP 2.2.3. |
| Test Item | Specification |
|---|---|
| Appearance | Off-white crystalline solid |
| Purity | >=98.0% (GC-MS) |
| Melting Point | 128–132°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Conforms to reference spectrum |
| Identification (IR) | Conforms to reference spectrum |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.