China Factory Direct
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| CAS number | 185331-69-5 |
| Product name | 1-Bromo-2-fluoro-4-nitrobenzene |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Chemicals | Pharmaceutical Intermediates | Serves as a key building block in the synthesis of drug molecules with specific biological activity, via nitro reduction, halogen substitution (fluorine or bromine), and coupling reactions. |
| Agrochemicals | Agrochemical Intermediates | Used to synthesize fluorinated and nitro-substituted aromatic agrochemical active ingredients through aromatic nucleophilic substitution to introduce functional groups. |
| Organic Synthesis | Substrate for Azole Compound Synthesis | Undergoes aromatic nucleophilic substitution with nitrogen-containing heterocycles (e.g., imidazole or pyrazole) in the presence of base to produce fluorinated nitrophenyl heterocyclic derivatives. |
| Research Reagents | Research & Development | Employed in synthetic methodology development (e.g., Suzuki coupling, Buchwald–Hartwig amination) and construction of molecular scaffolds for new drug screening. |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | Gas Chromatography (GC) with FID detection | Quantitative determination based on peak area comparison against a certified reference standard using a non-polar capillary column. |
| Related Substances | High Performance Liquid Chromatography (HPLC) with UV detection | Separation and quantification of impurities using reversed-phase C18 column and gradient elution with UV detection at 254 nm. |
| Residual Solvents | Gas Chromatography (GC) with Headspace sampling and FID | Headspace GC analysis to detect and quantify volatile organic solvents (e.g., acetone, methanol, toluene) based on calibrated external standards. |
| Water Content | Karl Fischer Titration (Coulometric mode) | Electrochemical titration where iodine generated in situ reacts stoichiometrically with water; measures trace moisture content. |
| Acid Value | Acid-Base Titration with NaOH standard solution | Neutralization of acidic impurities using standardized sodium hydroxide solution with phenolphthalein indicator or potentiometric endpoint detection. |
| Heavy Metals | Inductively Coupled Plasma Optical Emission Spectrometry (ICP-OES) | Multi-element quantitative analysis after acid digestion; detects metals (e.g., Pb, Cd, Hg, As) via element-specific emission lines. |
| Chloride Impurity | Ion Chromatography (IC) with conductivity detection | Separation of anions on an ion-exchange column followed by quantitative detection of chloride ions using suppressed conductivity. |
| Melting Point | Capillary Melting Point Apparatus | Thermal determination of solid-to-liquid transition range using calibrated digital apparatus per USP <741>. |
| Appearance | Visual Inspection in Standardized Light Box | Assessment of physical state, color, and clarity against white/black background under controlled D65 illumination. |
| Residue on Ignition | Gravimetric Analysis (Weight Loss on Ignition) | Measurement of non-volatile inorganic residue after controlled high-temperature ashing (700-800 C) and cooling in desiccator. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation of plane-polarized light caused by chiral impurities or degradation products in solution at specified concentration and wavelength (589 nm). |
| Particle Size Distribution | Laser Diffraction Particle Size Analyzer | Analysis of dry powder dispersion using Mie scattering theory to determine volumetric particle size distribution. |
| Test Item | Specification |
|---|---|
| Appearance | Yellow-brown solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Melting Point | 65–69 °C |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Identification (IR) | Consistent with structure |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.