China Factory Direct
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| CAS number | 185346-79-6 |
| Product name | 4-(Benzyloxy)-1-bromo-2-fluorobenzene |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Used in the synthesis of fluorinated aromatic compounds, including precursors to anticancer, anti-inflammatory, and central nervous system drugs | Multi-step organic synthesis, including palladium-catalyzed coupling reactions (e.g., Suzuki, Buchwald–Hartwig), nucleophilic substitution, and debenzylation |
| Agrochemical Intermediates | Serves as a fluorinated benzene ring building block for developing novel insecticides or herbicides | Synthetic processes including halogen exchange, arylation, and side-chain functionalization |
| Organic Synthesis Reagents | Functions as a versatile aromatic building block to introduce benzyloxy and fluorine groups, enabling synergistic modulation of molecular electronic properties and steric hindrance | Fine synthetic methods including Grignard reactions, lithium–halogen exchange, and transition-metal-catalyzed cross-coupling |
| Detection Item | Common Analytical Method | Method Overview |
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| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 254 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV against qualified reference standards or threshold-based reporting. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common solvents (e.g., methanol, toluene, DMF) based on calibrated external standards. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine generated electrochemically to react stoichiometrically with water in the sample. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (e.g., Pb, Cd, Hg, Ni) after acid digestion, using isotopic detection and internal standard correction. |
| Chloride Impurity | Ion Chromatography | Separation and conductivity detection of chloride ions after aqueous extraction and filtration. |
| Residual Palladium | ICP-OES | Quantification of palladium catalyst residue post-digestion by optical emission spectroscopy at characteristic wavelengths. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition observed visually or automatically as the temperature range over which solid-to-liquid phase change occurs. |
| Appearance | Visual Inspection | Assessment under controlled white light against a white/black background for color, clarity, and presence of particulates or foreign matter. |
| Bulk Density | USP <616> Tap Density Method | Determination of mass per unit volume after mechanical tapping of a known mass in a graduated cylinder. |
| Particle Size Distribution | Laser Diffraction | Analysis of scattered laser light intensity versus angle to calculate size distribution based on Mie scattering theory. |
| Optical Rotation | Polarimetry | Measurement of rotation of plane-polarized light by chiral components in solution at specified concentration and wavelength (e.g., 589 nm). |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Melting Point | 72-76°C |
| Water Content (KF) | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=20 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.