China Factory Direct
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| CAS number | 18598-63-5 |
| Product name | L-Cysteine methyl ester hydrochloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeFood GradeCosmetic Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Chiral intermediate for synthesis of pharmaceuticals, including antibiotics (e.g., cephalosporins), antiviral agents, and antioxidants | Used as a chiral auxiliary in asymmetric synthesis and peptide coupling reactions; hydrolyzed to L-cysteine under mild alkaline conditions |
| Food | Precursor for flavor enhancers, employed in the preparation of thermal reaction flavors (e.g., meat-type flavors) | Heated with reducing sugars in the Maillard reaction to release H₂S and sulfur-containing heterocyclic compounds, imparting roasted meat aroma |
| Cosmetics | Stabilizing carrier for active ingredients, used in sustained-release formulations of thiol-containing functional products | Thiol group protected via esterification to reduce oxidative sensitivity; active L-cysteine released upon enzymatic hydrolysis by esterases on the skin surface |
| Biochemical Research | Reagent for site-specific modification and crosslinking of proteins/peptides | Applied for selective thiol alkylation, disulfide bond reformation, or fluorescent labeling (e.g., reaction with maleimide derivatives) |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (L-Cysteine Methyl Ester Hydrochloride) | Acid-Base Titration | Quantifies active compound by titration with standardized NaOH using bromothymol blue indicator; endpoint corresponds to neutralization of HCl salt and carboxylic acid group. |
| Water Content | Karl Fischer Titration | Measures water via iodine-sulfur dioxide reaction in methanol-based reagent; coulometric or volumetric mode provides precise moisture quantification. |
| Optical Rotation | Polarimetry | Determines specific rotation using sodium D-line light; correlates with enantiomeric purity and chiral integrity of L-isomer. |
| Heavy Metals (as Pb) | Atomic Absorption Spectroscopy (AAS) | Quantifies total heavy metals after wet digestion by measuring absorbance of atomic vapor at characteristic wavelengths. |
| Residue on Ignition | Gravimetric Analysis | Measures inorganic ash content by ignition at 700-800 C followed by weighing of residual non-volatile material. |
| Chloride Content | Potentiometric Titration | Determines chloride ions using silver nitrate titrant and silver/silver chloride electrode; endpoint detected by potential inflection. |
| Related Substances | Reverse-Phase HPLC | Separates and quantifies impurities (e.g., L-cysteine, L-cystine, methyl ester hydrolysis products) using C18 column and UV detection at 210 nm. |
| pH (1% w/v aqueous solution) | pH Potentiometry | Measures hydrogen ion activity in aqueous solution using calibrated glass electrode and reference electrode. |
| Sulfate | Ion Chromatography (IC) | Quantifies sulfate anions by separation on anion-exchange column with suppressed conductivity detection. |
| Loss on Drying | Thermogravimetric Analysis (TGA) | Determines volatile content by measuring mass loss under controlled heating (105 C, 2 h) in air or nitrogen. |
| Microbial Limits | Membrane Filtration | Detects aerobic bacteria, yeast, and mold by filtration, membrane transfer to selective media, and colony enumeration after incubation. |
| Particle Size Distribution | Laser Diffraction | Measures particle size distribution in dry or liquid dispersion based on angular scattering pattern of laser beam. |
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Optical Rotation | -1.5 to -3.5 deg (c=1, H2O) |
| Melting Point | 178 to 182 °C |
| Heavy Metals | <=20 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.