China Factory Direct
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| CAS number | 18598-74-8 |
| Product name | Methyl L-isoleucinate hydrochloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthetic intermediate for drug synthesis | Used in the synthesis of peptide-based therapeutics and active pharmaceutical ingredients (APIs) as a chiral building block to introduce the isoleucine structure |
| Biochemical research | Preparation of amino acid derivatives | Applied in studies involving labeled amino acids or modified peptide chains, including enzyme substrate design and metabolic pathway analysis |
| Organic synthesis | Synthesis of chiral reagents and catalyst ligands | Employed as a chiral source in asymmetric synthesis to construct stereoselective molecular frameworks |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Separation on reversed-phase column with UV detection at 200-220 nm; quantification against reference standard |
| Related Substances | HPLC-UV | Gradient HPLC method to resolve and quantify structurally related impurities including diastereomers and degradation products |
| Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light in solution; confirms chiral integrity and enantiomeric excess |
| Loss on Drying | Gravimetric (105 C oven) | Mass loss after drying at 105 C for 2-3 hours; determines volatile content including residual solvents and water |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection for methanol, ethyl acetate, and other process solvents |
| Heavy Metals | ICP-MS | Quantitative determination of Pb, Cd, Hg, As, and other toxic elements by inductively coupled plasma mass spectrometry |
| Chloride Content | Potentiometric Titration | Titration with silver nitrate using silver indicator electrode; measures Cl- from hydrochloride salt counterion |
| Water Content | Karl Fischer Coulometric Titration | Electrochemical titration with iodine generation; specific and accurate for trace water determination |
| pH (1% aqueous solution) | Potentiometric pH Measurement | Measurement using calibrated pH electrode in 1% w/v aqueous solution at 25 C |
| Particle Size Distribution | Laser Diffraction | Analysis of scattered laser light intensity to determine volume-based particle size distribution |
| Microbial Limits | Membrane Filtration + Plate Count | Enumeration of aerobic microorganisms and absence testing for specified pathogens per pharmacopeial methods |
| Residue on Ignition | Gravimetric (500-600 C) | Mass of non-volatile inorganic residue remaining after high-temperature ashing; indicates inorganic impurities |
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% (NMR) |
| Water Content (KF) | <=0.5% |
| Melting Point | 148-152°C |
| Optical Rotation | +25.0 to +28.0° (c=1, in 1M HCl) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.