TERT-BUTYL 12-HYDROXY-4 7 10-TRIOXA- Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 186020-66-6 |
| Product name | TERT-BUTYL 12-HYDROXY-4 7 10-TRIOXA- |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25L/drum |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for TERT-BUTYL 12-HYDROXY-4 7 10-TRIOXA-
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk TERT-BUTYL 12-HYDROXY-4 7 10-TRIOXA- Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of TERT-BUTYL 12-HYDROXY-4 7 10-TRIOXA-
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Used as a drug synthesis intermediate for constructing prodrugs or targeted conjugates containing polyethylene glycol (PEG) chains | Applied as a bifunctional linker in solid-phase peptide synthesis (SPPS) for hydroxyl protection and PEGylation; the tert-butyl ester is cleaved under acidic conditions to release a free carboxylic acid, which is subsequently coupled to an active pharmaceutical ingredient |
| Bioconjugation Technology | Used for site-specific modification of proteins, antibodies, or nucleic acids to introduce PEG chains of controlled length, thereby improving pharmacokinetic properties | Coupled covalently to amino groups on biomacromolecule surfaces via NHS ester activation or EDC/DCC-mediated condensation; the tert-butyl ester group provides orthogonal protection compatible with Fmoc-SPPS conditions |
Manufacturing Quality Control of TERT-BUTYL 12-HYDROXY-4 7 10-TRIOXA-
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main compound by UV absorption at specific wavelength using reverse-phase chromatography with calibrated standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities using gradient HPLC separation and UV detection. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., THF, toluene) by gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Determines trace water via coulometric or volumetric titration based on iodine-sulfur dioxide redox reaction. |
| Acid Value | Acid-Base Titration | Measures free carboxylic acid groups by titration with standardized NaOH solution using phenolphthalein indicator. |
| Residue on Ignition | Gravimetric Analysis | Quantifies inorganic ash content after high-temperature incineration and weighing of residual residue. |
| Heavy Metals | ICP-OES | Detects toxic metals (e.g., Pb, Cd, Ni) by plasma excitation and elemental emission spectroscopy. |
| Chloride Content | Ion Chromatography | Separates and quantifies chloride ions using anion-exchange column and conductivity detection. |
| Optical Rotation | Polarimetry | Measures specific rotation using plane-polarized light to confirm chiral integrity and enantiomeric purity. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid, indicating crystallinity and purity. |
| Appearance | Visual Inspection | Assesses physical state, color, and clarity against defined standards under controlled lighting conditions. |
| Particle Size Distribution | Laser Diffraction | Measures size distribution of solid particles in suspension using angular scattering pattern analysis. |
Technical Specifications of TERT-BUTYL 12-HYDROXY-4 7 10-TRIOXA-
| Test Item | Specification |
|---|---|
| Appearance | Colorless liquid |
| Purity | >=98.0% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Acid Value (mg KOH/g) | <=1.0 mg KOH/g |
| Odor | Characteristic, mild |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of TERT-BUTYL 12-HYDROXY-4 7 10-TRIOXA-
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of TERT-BUTYL 12-HYDROXY-4 7 10-TRIOXA-
Safety Information of TERT-BUTYL 12-HYDROXY-4 7 10-TRIOXA-
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of TERT-BUTYL 12-HYDROXY-4 7 10-TRIOXA-
Industrial TERT-BUTYL 12-HYDROXY-4 7 10-TRIOXA- Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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