2-FLUORO-5-NITRO-6-PICOLINE Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 18605-16-8 |
| Product name | 2-FLUORO-5-NITRO-6-PICOLINE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2-FLUORO-5-NITRO-6-PICOLINE
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2-FLUORO-5-NITRO-6-PICOLINE Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2-FLUORO-5-NITRO-6-PICOLINE
| Industry | Application | Process |
|---|---|---|
| Pesticides | Critical intermediate for synthesizing novel insecticides (e.g., flupyradifurone) | Prepared via multi-step organic synthesis—including nitration and fluorination—to produce the target pesticide active ingredient |
| Pharmaceuticals | Used to construct fluorinated nitrogen-containing heterocyclic structures in drug candidates, such as kinase inhibitors | Serves as a starting material in coupling reactions (e.g., Suzuki, Heck) or reductive amination steps for drug molecule construction |
Manufacturing Quality Control of 2-FLUORO-5-NITRO-6-PICOLINE
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at ~254 nm. |
| Related Substances | HPLC-UV | Separation and detection of structurally related impurities (e.g., isomers, nitro-reduction products, unreacted intermediates) using gradient HPLC-UV. |
| Residual Solvents | GC-FID | Identification and quantification of volatile organic solvents (e.g., DMF, dichloromethane, toluene) by gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Coulometric or volumetric titration with iodine-based reagent to determine trace water based on stoichiometric reaction with iodine and sulfur dioxide. |
| Heavy Metals (Total) | ICP-OES | Multi-element quantification of toxic metals (e.g., Pb, Cd, Hg, As) after acid digestion, using inductively coupled plasma optical emission spectrometry. |
| Chloride Impurity | Ion Chromatography | Separation and conductivity detection of chloride ions eluted from an anion-exchange column following sample dissolution and filtration. |
| Sulfate Impurity | Ion Chromatography | Anion-exchange chromatography with suppressed conductivity detection for sulfate quantification in aqueous solution. |
| Melting Point | Capillary Melting Point Apparatus | Determination of solid-to-liquid transition temperature range using controlled heating of a capillary-packed sample. |
| Appearance | Visual Inspection | Assessment of physical state, color, and presence of foreign particles under standardized white light and against specified reference standards. |
| Loss on Drying | Gravimetric (Thermogravimetric) | Measurement of mass loss after drying under controlled temperature and vacuum or nitrogen purge to assess volatile content. |
| Residual Palladium | ICP-MS | Ultra-trace quantification of palladium catalyst residues after microwave-assisted digestion, using inductively coupled plasma mass spectrometry. |
| Optical Rotation | Polarimetry | Measurement of specific rotation using sodium D-line light to confirm chiral purity (if applicable) or detect enantiomeric contamination. |
Technical Specifications of 2-FLUORO-5-NITRO-6-PICOLINE
| Test Item | Specification |
|---|---|
| Appearance | Yellow liquid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Melting Point | -15 to -10 °C |
| Odor | Characteristic odor |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2-FLUORO-5-NITRO-6-PICOLINE
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2-FLUORO-5-NITRO-6-PICOLINE
Packaging of 2-FLUORO-5-NITRO-6-PICOLINE
Industrial 2-FLUORO-5-NITRO-6-PICOLINE Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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