3-Hydroxyazetidine hydrochloride Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 18621-18-6 |
| Product name | 3-Hydroxyazetidine hydrochloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 3-Hydroxyazetidine hydrochloride
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 3-Hydroxyazetidine hydrochloride Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 3-Hydroxyazetidine hydrochloride
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Chiral building block for synthesizing antiviral agents (e.g., HCV NS5A inhibitors) and kinase inhibitors | Introduced as an azetidine structural unit in coupling reactions, followed by multi-step synthesis including amination and acylation |
| Pharmaceuticals | Construction of drug candidate molecules containing an azetidine scaffold | Coupled with aldehyde or ketone substrates via nucleophilic substitution or reductive amination |
| Agrochemicals | Intermediate in molecular design of novel insecticides and fungicides | Used to synthesize active compounds bearing azetidine side chains to enhance metabolic stability |
| Materials Science | Functional monomer for preparing high-refractive-index optical resins | Undergoes condensation or addition polymerization with diacids or isocyanates to incorporate azetidine units into polymer backbones |
Manufacturing Quality Control of 3-Hydroxyazetidine hydrochloride
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at 210 nm, calibrated against certified reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities using gradient HPLC-UV; identification based on retention time comparison. |
| Water Content | Karl Fischer Titration | Determines water by coulometric or volumetric titration using iodine generated electrochemically in methanol-based reagent. |
| Residue on Ignition | Gravimetric Analysis | Measures non-volatile inorganic residue after incineration at 700-800 C and subsequent weighing. |
| Heavy Metals | ICP-OES | Quantifies Pb, Cd, Hg, As, and other regulated metals via plasma emission spectroscopy after acid digestion. |
| Chloride Content | Potentiometric Titration | Titrates chloride ions with silver nitrate using silver/silver chloride electrode for endpoint detection. |
| pH (1% w/v aqueous solution) | pH Potentiometry | Measures hydrogen ion activity using calibrated glass electrode in aqueous solution at 25 C. |
| Specific Optical Rotation | Polarimetry | Determines chiral purity by measuring rotation of plane-polarized light at 589 nm using sodium D-line. |
| Loss on Drying | Thermogravimetry | Quantifies volatile matter by weight loss after drying at 105 C under vacuum for 2 hours. |
| Particle Size Distribution | Laser Diffraction | Analyzes dry powder size distribution by measuring angular scattering pattern of laser beam. |
| Microbial Limits | Membrane Filtration | Detects aerobic microorganisms and specified pathogens using filtration, culture, and colony enumeration. |
| Residual Solvents | GC-FID | Identifies and quantifies residual solvents (e.g., methanol, acetone) using gas chromatography with flame ionization detection. |
Technical Specifications of 3-Hydroxyazetidine hydrochloride
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 145-149°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 3-Hydroxyazetidine hydrochloride
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 3-Hydroxyazetidine hydrochloride
Safety Information of 3-Hydroxyazetidine hydrochloride
| Pictograms |  |
| Signal Word | Danger |
| Safety Data Sheet | |
Packaging of 3-Hydroxyazetidine hydrochloride
Industrial 3-Hydroxyazetidine hydrochloride Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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