China Factory Direct
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| CAS number | 186496-59-3 |
| Product name | 5-FLUORO-2-METHYLPHENYLMAGNESIUM BROMIDE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Synthesis | Used as a Grignard reagent to construct fluorinated aryl ring structures for drug intermediate synthesis | Grignard reaction; coupled with aldehydes, ketones, or organic halides to generate complex organic molecules |
| Organic Synthesis | Introduces the 5-fluoro-2-methylphenyl functional group to build C–C bonds | Nucleophilic addition or transition-metal-catalyzed cross-coupling (e.g., Kumada coupling) |
| Pesticide Development | Serves as a precursor for novel fluorinated aromatic active pharmaceutical ingredients in pesticide development | Reacted with heterocyclic or carbonyl compounds to construct target molecular frameworks |
| Materials Science | Used to prepare fluorinated functional aromatic polymers or liquid crystal monomers | Fluoroaryl side chains introduced via coupling or polymerization reactions |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Main Component) | GC-FID or GC-MS | Quantitative determination of 5-fluoro-2-methylphenylmagnesium bromide by comparison to a reference standard using gas chromatography with flame ionization or mass spectrometric detection. |
| Residual Solvent (THF) | GC-FID | Separation and quantification of tetrahydrofuran content based on retention time and peak area relative to calibration standards. |
| Water Content | Karl Fischer Titration | Electrochemical titration measuring water via reaction with iodine, sulfur dioxide, and base in anhydrous methanol/pyridine medium. |
| Mg Content | ICP-OES | Quantification of total magnesium concentration after acid digestion and plasma excitation, measuring characteristic atomic emission lines. |
| Halide Impurities (Br-, Cl-) | Ion Chromatography (IC) | Separation of anions on an ion-exchange column followed by conductivity detection and quantification against calibration standards. |
| Organic Impurities (Related Substances) | HPLC-UV | Separation of structurally related compounds using reversed-phase chromatography and UV absorbance detection at specified wavelength. |
| Acid-Neutralizing Value (ANV) | Acid-Base Titration | Titration with standardized HCl to determine active Grignard species concentration via proton consumption stoichiometry. |
| Appearance | Visual Inspection | Assessment of solution clarity, color, and presence of suspended particles or phase separation under controlled lighting conditions. |
| pH (Aqueous Hydrolysate) | pH Meter Measurement | Measurement of pH after controlled hydrolysis and dilution to assess residual acidic/basic impurities. |
| Heavy Metals (Pb, Cd, Ni, Fe) | ICP-MS | Multi-element quantification after microwave-assisted digestion using high-sensitivity mass spectrometric detection of metal isotopes. |
| Residual Magnesium Oxide/Hydroxide | Gravimetric Analysis | Precipitation as MgNH4PO4, ignition to Mg2P2O7, and weighing to determine insoluble magnesium species. |
| Stability Indicating Parameters (Decomposition Products) | GC-MS | Identification and semi-quantification of thermal or hydrolytic degradation products using retention time and mass spectral library matching. |
| Test Item | Specification |
|---|---|
| Appearance | Colorless to pale yellow solution in tetrahydrofuran |
| Purity | >=98.0% |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Identification (NMR) | Conforms to reference standard |
| Odor | Characteristic mild ether-like odor |
| Solubility | Miscible with THF, diethyl ether; insoluble in water |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.