China Factory Direct
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| CAS number | 18650-38-9 |
| Product name | (R)-Piperidine-2-carboxylic acid methyl ester hydrochloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Chiral intermediates for synthesizing biologically active piperidine-containing drugs (e.g., antidepressants, antipsychotics, analgesics) | Used as a chiral building block in asymmetric synthesis, amidation, and reductive amination |
| Agrochemicals | Intermediates for synthesizing chiral pesticides or plant growth regulators | Integrated into target molecular frameworks via multistep organic synthesis |
| Fine Chemicals | Precursors for chiral ligands or catalysts | Applied in constructing nitrogen-containing heterocyclic ligands for metal-catalyzed reaction systems |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification using reverse-phase HPLC with UV detection at 210 nm, relative to a certified reference standard. |
| Enantiomeric Purity | Chiral HPLC | Separation of (R)- and (S)-enantiomers on a chiral stationary phase, with UV detection and peak area ratio calculation. |
| Water Content | Karl Fischer Titration | Volumetric titration using iodine, sulfur dioxide, and base in methanol-based reagent; measures total water by coulometric or volumetric reaction stoichiometry. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection, quantifying common solvents (e.g., methanol, dichloromethane) against calibration standards. |
| Heavy Metals | ICP-MS | Multi-element quantification of Pb, Cd, Hg, As, and others after acid digestion, based on isotopic mass spectrometry detection. |
| Chloride Content | Potentiometric Titration | Titration with silver nitrate using a silver indicator electrode; endpoint detected by potential inflection. |
| Residue on Ignition | Gravimetric Analysis | Weighing residue remaining after controlled high-temperature ashing (700-800 C) of sample in platinum crucible. |
| pH of Aqueous Solution | pH Meter Measurement | Direct measurement of pH in a 1% w/v aqueous suspension using calibrated pH meter with glass electrode. |
| Appearance | Visual Inspection | Assessment of crystalline form, color, and absence of visible particulates or discoloration under controlled white light. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid transitions to liquid, using calibrated digital melting point instrument. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light at 20 C using sodium D-line (589 nm), reported as [alpha]D. |
| Related Substances | HPLC-UV | Detection and quantification of structurally related impurities (e.g., hydrolysis products, diastereomers) using gradient reverse-phase HPLC. |
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 148–152 °C |
| Optical Rotation | +8.5 to +9.5 ° (c=1, in methanol) |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.