China Factory Direct
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| CAS number | 186590-43-2 |
| Product name | 5-bromo-2-chloro-3-fluorophenol |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty GradeElectronic GradeMaterial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pesticides | Intermediate for synthesizing novel fluorinated fungicides and insecticides | Used to construct the active molecular scaffold via electrophilic substitution and halogen exchange, followed by coupling with nitrogen- or sulfur-containing functional groups |
| Pharmaceuticals | Aromatic intermediate for synthesizing antiviral and antitumor drugs | Applied as a key building block in Suzuki coupling, Ullmann coupling, or nucleophilic substitution to introduce the phenolic moiety into drug molecules |
| Dyes and Pigments | Precursor for high-performance fluorinated azo dyes | After diazotization, condensed with phenols or amines to produce colored compounds exhibiting high lightfastness and stability |
| Electronic Chemicals | Intermediate for organic semiconductor materials and liquid crystal compounds | Employed in metal-catalyzed coupling reactions to introduce conjugated structures for synthesizing fluorinated aromatic liquid crystals or hole-transport materials |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reverse-phase HPLC with UV detection at 220-280 nm based on peak area comparison against reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities (e.g., isomers, dehalogenated by-products) using gradient HPLC-UV with system suitability criteria. |
| Residual Solvents | GC-FID | Measures trace organic solvents (e.g., methanol, toluene, THF) by gas chromatography with flame ionization detection using headspace sampling. |
| Water Content | Karl Fischer Titration | Determines water content via coulometric or volumetric titration using iodine generation in pyridine-free reagent system. |
| Heavy Metals | ICP-MS | Quantifies toxic elements (Pb, Cd, Hg, As) after acid digestion using inductively coupled plasma mass spectrometry for sub-pptr detection. |
| Chloride Content | Ion Chromatography | Separates and quantifies chloride ions using suppressed conductivity detection after sample dissolution and filtration. |
| Melting Point | Capillary Melting Point Apparatus | Measures temperature range at which solid transitions to liquid using calibrated capillary apparatus per USP <741>. |
| Appearance | Visual Inspection | Assesses physical state, color, and presence of visible particulates or discoloration against white background under controlled lighting. |
| Residue on Ignition | Gravimetric Analysis | Determines inorganic ash content by ignition at 500-600 C followed by precise weighing of residual residue. |
| Acid Value | Acid-Base Titration | Measures free acidic impurities by titration with standardized NaOH solution using phenolphthalein indicator. |
| Particle Size Distribution | Laser Diffraction | Analyzes dry powder particle size distribution using Mie theory-based light scattering from dispersed aerosolized sample. |
| Specific Optical Rotation | Polarimetry | Determines chiral purity (if applicable) by measuring rotation angle of plane-polarized light at specified wavelength and concentration. |
| Test Item | Specification |
|---|---|
| Appearance | Gray to brown solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Melting Point | 65–69 °C |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Conforms to reference spectrum |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.