China Factory Direct
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| CAS number | 18704-37-5 |
| Product name | 8-Quinolinesulfonyl chloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate for synthesizing antimalarial drugs (e.g., chloroquine analogues) | Used to construct sulfonamide bonds via nucleophilic substitution with amines |
| Pesticides | Preparation of sulfonyl-containing insecticides and fungicides | Applied as a sulfonylation reagent for functionalization of heterocyclic compounds |
| Dyes | Synthesis of fluorescent brighteners and metal-complex dyes | Introduces water-solubilizing or coordinating groups via the sulfonyl chloride moiety to enhance dye performance |
| Materials Science | Preparation of electron-transport materials for organic light-emitting diodes (OLEDs) | Converted into quinoline-based sulfonamides or sulfonate esters with high electron affinity via amination or alcoholysis |
| Test Item | Common Testing Method | Method Overview |
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| Appearance | Visual Inspection | Observe the color and condition of the sample (e.g., white to pale yellow crystalline powder), whether it is clumped or contains visible impurities. |
| Purity (Main Component Content) | High-Performance Liquid Chromatography (HPLC) | Using a reverse-phase C18 chromatography column and a UV detector (usually at 254 nm or according to the maximum absorption wavelength), determine the content of the target compound using external standard method or area normalization method to assess purity. |
| Chlorine Content (Active Chlorine) | Chloride Titration Method (e.g., Argentometric Method) | Hydrolyze the sample to release chloride ions, which are then titrated with a standard silver nitrate solution using potassium chromate as an indicator. Calculate the effective chlorine content, indirectly reflecting the integrity of the sulfonyl chloride group. |
| Moisture | Karl Fischer Titration | Determine the moisture content in the sample through an electrochemical reaction, suitable for trace moisture detection, ensuring product dryness and stability. |
| Residual Solvents | Gas Chromatography (GC) | Use capillary columns and FID detectors to detect residual organic solvents (such as toluene, dichloromethane, etc.) from the production process, meeting ICH limit requirements. |
| Melting Point | Melting Point Determination (Capillary Method or Automatic Melting Point Instrument) | Determine the temperature range at which the compound transitions from solid to liquid, used for preliminary judgment of material purity and consistency. |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Separate the main peak from impurity peaks using gradient elution, detect and quantify degradation products or by-products (such as hydrolyzed quinoline-8-sulfonic acid). |
| Infrared Spectroscopy (IR) | Fourier Transform Infrared Spectroscopy (FT-IR) | Compare with standard spectra to confirm the presence of characteristic functional groups (such as S=O, C-Cl, aromatic rings), used for structural confirmation and authenticity identification. |
| Nuclear Magnetic Resonance (NMR) | ¹H-NMR and ¹³C-NMR | Determine proton and carbon spectra in deuterated solvents to verify molecular structure and identify impurity signals, commonly used for standard samples or key batch confirmation. |
| Test Item | Specification |
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| Appearance | White to orange to green crystalline powder |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 65–69°C |
| Identification (NMR) | Consistent with structure |
| Identification (IR) | Consistent with structure |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.