China Factory Direct
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| CAS number | 18706-33-7 |
| Product name | 4,6-DICHLORO-2-(TRIFLUOROMETHYL)QUINOLINE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pesticides | Bactericide intermediate for synthesizing quinoline-based bactericides (e.g., fluazinam analogues) | Undergoes nucleophilic substitution with aniline derivatives to construct quinoline heterocyclic derivatives |
| Pharmaceuticals | Structural building block in antibacterial drug development, used to construct candidate molecules containing a trifluoromethylquinoline scaffold | Introduces aryl or alkenyl substituents via palladium-catalyzed cross-coupling (e.g., Suzuki or Heck reactions), followed by functional group transformations |
| Materials Science | Precursor for organic optoelectronic materials, used to prepare quinoline-based small-molecule semiconductors with electron-transport properties | Reacts with lithium metal or Grignard reagents under inert atmosphere to generate lithiated/magnesiated intermediates, which subsequently condense with electrophilic carbonyl compounds (e.g., aldehydes or ketones) to build conjugated systems |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 254 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-DAD | Separation and identification of impurities using HPLC coupled with diode-array detection; relative retention times and spectral matching support qualification. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common solvents (e.g., methanol, acetone, toluene) based on calibrated external standards. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine generation in pyridine-free reagent; measures water via stoichiometric reaction with iodine and sulfur dioxide. |
| Heavy Metals (as Pb) | ICP-OES | Multi-element quantification after acid digestion; detects metals by measuring atomic emission intensities at characteristic wavelengths. |
| Chloride Impurity | Ion Chromatography | Separation of anions on anion-exchange column with suppressed conductivity detection; quantifies chloride using external calibration. |
| Residue on Ignition | Gravimetric Analysis | Weighing residue remaining after controlled high-temperature ashing (700-800 C) to assess inorganic ash content. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition observed visually or automatically as the solid-to-liquid phase change range under controlled heating rate. |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity of neat sample against defined standards (e.g., white to off-white crystalline powder). |
| Particle Size Distribution | Laser Diffraction | Measurement of scattered laser light intensity at multiple angles to calculate particle size distribution based on Mie theory. |
| Bulk Density | Graduated Cylinder Method | Mass per unit volume determined by gently pouring material into a calibrated cylinder and measuring settled volume. |
| Organic Volatile Impurities (OVI) | GC-MS | Identification and quantification of trace volatile organics using gas chromatography coupled with mass spectrometry for selective detection. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.3% |
| Melting Point | 124–128°C |
| Water Content (KF) | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=20 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.