China Factory Direct
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| CAS number | 18740-39-1 |
| Product name | 2,4-Dichlorothieno[2,3-d]pyrimidine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pesticides | Intermediate for herbicides, used in the synthesis of thienopyrimidine herbicides (e.g., pyribenzoxim, bispyribac-sodium) | Undergoes nucleophilic substitution with aromatic amines or phenols under basic conditions to construct the pyrimidine ring side chain; alternatively participates in heterocycle formation via oxidation, coupling, and related steps |
| Pharmaceuticals | Structural motif for antibacterial and antiviral drug candidates | Used to construct biologically active thienopyrimidine heterocyclic scaffolds, commonly applied in medicinal chemistry for structural modification and structure–activity relationship studies |
| Organic Synthesis | Intermediate for heterocyclic functional materials and fluorescent probe molecules | Introduces conjugated groups—such as via lithiation–borylation, Suzuki coupling, or Pd-catalyzed cross-coupling—to extend the π-conjugated system |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification using reverse-phase HPLC with UV detection at characteristic wavelength, calibrated against certified reference standard. |
| Related Substances | HPLC-DAD or HPLC-MS | Separation and identification of impurities based on retention time and spectral/mass data relative to main peak. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify volatile organic solvents per ICH Q3C guidelines. |
| Water Content | Karl Fischer Titration | Electrochemical titration using iodine-based reagent to determine trace water content in sample. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (e.g., Pb, Cd, Hg, As) after acid digestion and isotopic detection. |
| Chloride Content | Potentiometric Titration | Titration with silver nitrate using silver indicator electrode to measure total chloride ion concentration. |
| Melting Point | Capillary Melting Point Apparatus | Thermal determination of solid-to-liquid transition range using calibrated capillary apparatus per USP <741>. |
| Appearance | Visual Inspection | Assessment of physical state, color, and presence of foreign particles under controlled lighting and white background. |
| Residue on Ignition | Gravimetric Analysis | Weighing of non-volatile residue after high-temperature ashing at 600-800 C in platinum crucible. |
| Particle Size Distribution | Laser Diffraction | Measurement of size distribution in dispersed powder sample using Mie scattering theory and optical detection. |
| pH of Aqueous Suspension | pH Meter | Measurement of hydrogen ion activity in a standardized suspension (e.g., 1% w/v in water) using calibrated pH electrode. |
| Specific Optical Rotation | Polarimetry | Determination of chiral rotation angle using sodium D-line light through a solution in specified solvent and path length. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline solid |
| Purity | >=98.5% (by LC-MS) |
| Melting Point | 142–146 °C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Conforms to reference spectrum |
| Heavy Metals | <=20 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Danger |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.