China Factory Direct
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| CAS number | 1878-69-9 |
| Product name | 3-Iodophenylacetic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthesis of antitumor drug intermediates | Grignard reaction, iodination |
| Agrochemicals | Preparation of herbicide intermediates | Alkylation, esterification |
| Chemicals | Production of liquid crystal material intermediates | Iodoarene coupling reaction |
| Pharmaceuticals | Intermediate for cardiovascular drug synthesis | Esterification, amidation |
| Test Item | Common Test Methods | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the sample's color, physical state (e.g., white or off-white crystalline powder), and presence of visible impurities with the naked eye to determine compliance with quality specifications. |
| Identification | Infrared Spectroscopy (IR) High-Performance Liquid Chromatography (HPLC) Proton Nuclear Magnetic Resonance (¹H NMR) |
- IR: Record the infrared absorption spectrum of the sample and compare it with that of a reference standard to confirm characteristic functional groups (e.g., carboxyl, aromatic ring, C–I bond); - HPLC: Compare the retention time of the sample with that of the reference standard under specified chromatographic conditions; - ¹H NMR: Analyze chemical shifts and coupling constants of hydrogen atoms to verify molecular structural features. |
| Assay | High-Performance Liquid Chromatography (HPLC) | Use a reversed-phase C18 column with methanol-water or acetonitrile-water as the mobile phase and a UV detector (typically at around 254 nm) to detect 3-iodophenylacetic acid. Calculate the content using external standard or area normalization method to ensure purity meets specifications (typically ≥98.0%). |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Under the same or optimized chromatographic conditions as used in the assay, detect and quantify potential organic impurities (e.g., unreacted starting materials, by-products, degradation products). Use the standard substance comparison method or main component self-comparison method with correction factors to control limits for individual and total impurities. |
| Loss on Drying | Thermogravimetric Analysis (TGA) or Constant Temperature Atmospheric Drying | Dry the sample at 105°C to constant weight and measure the percentage weight loss to control moisture and volatile content (typically required ≤0.5%). |
| Sulfated Ash | High-Temperature Incineration | Treat the sample with sulfuric acid, then incinerate at 700–800°C to constant weight. Measure the residual inorganic matter (ash) to control inorganic impurities (typically required ≤0.1%). |
| Heavy Metals | Thioacetamide Method (Colorimetry) or Inductively Coupled Plasma Mass Spectrometry (ICP-MS) | - Colorimetry: In acidic conditions, heavy metals react with thioacetamide to form colored precipitates, which are compared to a standard lead solution; - ICP-MS: Highly sensitive quantitative determination of elemental impurities such as lead, mercury, cadmium, and arsenic; suitable for strict control of metal residues. |
| pH (if prepared as a solution) | pH Meter Method | Dissolve the sample in water to a specified concentration (e.g., 1%), and measure the pH using a calibrated pH meter to evaluate acidity and the presence of acidic or basic impurities. |
| Test Item | Specification |
|---|---|
| Appearance | Off-white crystalline solid |
| Purity | >=98.0% (by LC-MS) |
| Melting Point | 142–146 °C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.