O-tert-Butyl-L-tyrosine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 18822-59-8 |
| Product name | O-tert-Butyl-L-tyrosine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for O-tert-Butyl-L-tyrosine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk O-tert-Butyl-L-tyrosine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of O-tert-Butyl-L-tyrosine
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Used as a non-natural amino acid in peptide drug synthesis and modification to enhance metabolic stability or receptor selectivity | Introduced as a building block into the target peptide chain via solid-phase or liquid-phase peptide synthesis (SPPS/LPPS) |
| Biochemical Research | Applied in protein engineering and enzymology studies to investigate tyrosine site functionality or modulate protein–ligand interactions | Site-specifically incorporated into proteins using genetic code expansion or chemical synthesis methods |
| Organic Synthesis | Employed as a chiral intermediate or protected tyrosine derivative in complex molecule construction | Utilizes the tert-butyl ether moiety to protect the phenolic hydroxyl group, enabling selective reactions in multistep syntheses |
Manufacturing Quality Control of O-tert-Butyl-L-tyrosine
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at ~220 nm, comparing peak area against a certified reference standard. |
| Chiral Purity | Chiral HPLC | Enantiomeric excess assessment using a chiral stationary phase; separation based on stereospecific interactions with the L-enantiomer. |
| Residual Solvents | GC-FID | Identification and quantification of volatile organic solvents (e.g., methanol, THF, ethyl acetate) via gas chromatography with flame ionization detection. |
| Heavy Metals | ICP-MS | Multi-element trace metal quantification (e.g., Pb, Cd, Ni, Fe) after acid digestion, leveraging high sensitivity and isotopic resolution. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration measuring water via stoichiometric reaction with iodine in pyridine/methanol medium. |
| Residue on Ignition | Gravimetric Analysis | Determination of inorganic ash content by incineration at 700–800 °C followed by precise weighing of residual residue. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light at 20 °C using sodium D-line (589 nm), confirming chiral integrity and concentration. |
| Related Substances | HPLC-UV (Forced Degradation Compatible) | Detection and quantification of structurally related impurities (e.g., de-tert-butylation product, diketopiperazine) using gradient RP-HPLC. |
| pH (1% w/v aqueous suspension) | pH Meter | Electrochemical measurement of hydrogen ion activity in a standardized aqueous suspension, reflecting acid-base character. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry or wet dispersed sample to determine volumetric particle size distribution based on light scattering patterns. |
| Microbial Limits | Membrane Filtration + Culture | Enumeration of aerobic microorganisms and absence testing for specified pathogens (e.g., E. coli, S. aureus) per USP <61> and <62>. |
Technical Specifications of O-tert-Butyl-L-tyrosine
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 245-249°C |
| Optical Rotation | -4.0 to -9.0° (c=1, 1M HCl) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of O-tert-Butyl-L-tyrosine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of O-tert-Butyl-L-tyrosine
Packaging of O-tert-Butyl-L-tyrosine
Industrial O-tert-Butyl-L-tyrosine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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