China Factory Direct
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| CAS number | 188646-83-5 |
| Product name | 4-(Dimethoxymethyl)-piperidine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25L/drum |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Intermediate for synthesizing antiviral, antitumor, or neurology-related drugs | Introduces the piperidine moiety via nucleophilic substitution, reductive amination, or condensation reactions in multistep organic synthesis |
| Organic Synthesis | Nitrogen-containing heterocyclic building block for constructing complex molecular frameworks | Undergoes functional group transformations under palladium-catalyzed coupling, Boc protection/deprotection, and related conditions |
| Drug Discovery | Development of novel GPCR-targeting ligands or enzyme inhibitors | Condenses with carboxylic acids or aldehydes/ketones to form amide or imine bonds, optimizing pharmacophore structure |
| Detection Item | Common Analytical Method | Method Overview |
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| Assay (Purity) | HPLC-UV | Quantitative determination based on peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at ~210 nm. |
| Related Substances | HPLC-UV or UPLC-MS | Separation and identification/quantification of structurally related impurities (e.g., dealkylated, hydrolyzed, or oxidized derivatives) using gradient elution and spectral confirmation (MS) or retention time matching (UV). |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify residual solvents (e.g., methanol, dichloromethane, toluene) against calibrated standards per ICH Q3C guidelines. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration measuring water via iodine generation and stoichiometric reaction with water in anhydrous methanol-based electrolyte. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic elements (e.g., Pb, Cd, Hg, As) after acid digestion, offering sub-ppt detection limits compliant with ICH Q3D. |
| Optical Rotation | [α]D | Measurement of specific rotation using a digital polarimeter at 20 °C and sodium D-line (589 nm) to confirm chiral integrity and enantiomeric purity. |
| Residue on Ignition | Gravimetric Analysis | Determination of inorganic ash content after controlled high-temperature incineration (700–800 °C) and precise weighing of residue. |
| pH (10% w/v aqueous solution) | Potentiometric pH Measurement | Direct measurement using calibrated glass electrode in a saturated aqueous suspension or clarified solution per USP <791>. |
| Test Item | Specification |
|---|---|
| Appearance | Colorless liquid |
| Purity | >=98.0% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Odor | Characteristic odor |
| Refractive Index (n20/D) | 1.465–1.475 |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Danger |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.