China Factory Direct
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| CAS number | 188723-58-2 |
| Product name | 5-Chloro-2-fluorobenzyl alcohol |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
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| Pharmaceutical Intermediates | Key intermediate in the synthesis of the antifungal drug voriconazole | Prepared by selective reduction of 5-chloro-2-fluorobenzoic acid or its esters (e.g., methyl ester) under anhydrous conditions, commonly using lithium aluminum hydride (LiAlH₄) or sodium borohydride (NaBH₄) with a catalyst; alternatively obtained via alkaline hydrolysis or silver oxide-catalyzed hydrolysis of 5-chloro-2-fluorobenzyl chloride |
| Pesticide Intermediates | Structural building block for synthesizing novel fluorinated benzyl alcohol-based insecticides and fungicides | Serves as a starting material in halogen exchange, nitration, and coupling reactions to construct fluorinated heterocycles or substituted phenyl side chains; frequently employed in lead compound optimization for triazole- and pyrimidine-based pesticide candidates |
| Organic Synthesis | Building block for chloro- and fluoro-substituted benzyl alcohol scaffolds, used in ligand design and functional material molecule synthesis | Oxidized to the corresponding aldehyde or carboxylic acid; or subjected to halogenation/sulfonylation followed by Suzuki, Heck, and other cross-coupling reactions; also applied in chiral derivatization to prepare precursors for asymmetric catalysis ligands |
| Detection Item | Common Analytical Method | Method Overview |
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| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 220-254 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-DAD | Separation and identification of impurities by HPLC coupled with diode array detection; relative retention times and UV spectra support structural assignment. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify volatile organic solvents based on calibrated response factors. |
| Water Content | Karl Fischer Titration | Electrochemical titration using iodine, sulfur dioxide, and base in methanol medium; endpoint detected potentiometrically. |
| Chloride Impurity | Ion Chromatography (IC) | Separation of chloride anions on anion-exchange column with conductivity detection, quantified against external calibration standards. |
| Heavy Metals | ICP-OES | Multi-element quantification after acid digestion using inductively coupled plasma optical emission spectrometry with wavelength-specific emission detection. |
| Acid Value | Acid-Base Titration | Neutralization of acidic impurities with standardized NaOH solution using phenolphthalein indicator; calculated as mg KOH per g sample. |
| Residue on Ignition | Gravimetric Analysis | Ignition of sample at 700-800 C followed by weighing of non-volatile inorganic residue. |
| Optical Rotation | Polarimetry | Measurement of rotation of plane-polarized light through a solution of the compound in specified solvent and path length. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range over which solid transitions to liquid using controlled heating and visual observation. |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity against standard references under controlled lighting conditions. |
| pH of Aqueous Solution | pH Meter | Measurement of hydrogen ion activity in a saturated aqueous suspension using calibrated glass electrode system. |
| Test Item | Specification |
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| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Melting Point | 68–72°C |
| Water Content (KF) | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=20 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.