China Factory Direct
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| CAS number | 1892-57-5 |
| Product name | 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical GradeMaterial GradeSpecialty Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Biotechnology | Crosslinking of proteins and peptides | Used as a carbodiimide coupling agent to activate carboxyl groups under pH 4.5–7.5, enabling stable amide bond formation with amino groups |
| Pharmaceutical R&D | Drug molecule conjugation and modification | Applied to covalently link drug molecules to carrier proteins, antibodies, or targeting moieties |
| Biomaterials | Hydrogel fabrication and surface functionalization | Activates carboxyl-containing polymers (e.g., sodium alginate, polyacrylic acid) for crosslinking with amino-containing materials (e.g., chitosan) to form network structures |
| Diagnostics | Enzyme immobilization and immunoassay platform construction | Immobilizes antibodies or enzymes onto magnetic beads, microtiter plates, or sensor surfaces via carboxyl–amino coupling |
| Agrochemicals | Pesticide molecule conjugation and controlled-release system synthesis | Used to link active ingredients to polymeric carriers to enhance release profile characteristics |
| Polymer Chemistry | Polymer modification and grafting | Activates carboxyl-containing polymers (e.g., polyesters, polyacids) for graft modification with amine-based monomers |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 200-220 nm, comparing peak area to a certified reference standard. |
| Water Content | Karl Fischer Titration | Electrochemical titration measuring water via iodine-sulfur dioxide reaction in anhydrous methanol-based solvent. |
| Residual Solvents | GC-FID | Separation and quantification of volatile solvents (e.g., dichloromethane, toluene) using capillary GC with flame ionization detection. |
| Heavy Metals | ICP-OES | Multi-element detection after acid digestion, based on atomic emission intensities at element-specific wavelengths. |
| Chloride Impurity | Ion Chromatography | Separation of chloride anions on an anion-exchange column with conductivity detection. |
| Related Substances | HPLC-UV | Identification and quantification of structurally related impurities (e.g., urea derivatives, hydrolysis products) using gradient HPLC-UV. |
| Acid Value | Acid-Base Titration | Titration with standardized NaOH solution using phenolphthalein indicator to determine free carboxylic acid content. |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity against established reference standards under controlled lighting. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid transitions to liquid using calibrated capillary apparatus. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light induced by chiral centers in solution at specified concentration and wavelength. |
| Residue on Ignition | Gravimetric Analysis | Weighing residue remaining after high-temperature ashing to assess inorganic impurity load. |
| pH (1% w/v aqueous solution) | pH Meter | Electrochemical measurement of hydrogen ion activity in a standardized aqueous suspension using calibrated pH electrode. |
| Test Item | Specification |
|---|---|
| Appearance | Colorless to pale yellow liquid |
| Purity | >=98.0% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Identification (NMR) | Conforms to reference spectrum |
| Odor | Characteristic amine-like odor |
| Refractive Index (n20/D) | 1.465–1.475 |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() ![]() ![]() ![]() |
| Signal Word | Danger |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.