4,5-Difluorophthalic acid Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 18959-31-4 |
| Product name | 4,5-Difluorophthalic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Electronic GradeMaterial GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4,5-Difluorophthalic acid
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4,5-Difluorophthalic acid Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4,5-Difluorophthalic acid
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Used in the synthesis of fluorinated pharmaceutical molecules, such as antitumor or antimicrobial compounds | Serves as a building block in multistep organic synthesis to introduce fluorine substituents for modulating biological activity |
| Electronic Materials | Used in the preparation of high-performance polyimide (PI) materials | Undergoes condensation polymerization with diamine monomers to yield fluorinated polyimides, enhancing thermal stability and dielectric properties |
| Liquid Crystal Materials | Serves as a precursor to liquid crystal monomers for display devices | Introduces rigid fluorinated aryl ring structures via esterification or amidation reactions to improve liquid crystalline phase behavior and response speed |
| Organic Synthesis | Acts as a fluorinated aromatic carboxylic acid in coordination or functionalization reactions | Applied in the synthesis of metal–organic frameworks (MOFs) or catalyst ligands to enhance structural stability and selectivity |
Manufacturing Quality Control of 4,5-Difluorophthalic acid
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 230-254 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification based on retention time matching and threshold limits per ICH Q3A. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common solvents (e.g., methanol, acetone, DMF) against calibrated standards. |
| Moisture Content | Karl Fischer Titration | Volumetric or coulometric titration with iodine-based reagent to determine water content by stoichiometric reaction. |
| Heavy Metals | ICP-OES | Multi-element quantification of Pb, Cd, Hg, As, and others after acid digestion, using plasma optical emission spectroscopy. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of chloride ions using suppressed conductivity detection after aqueous extraction. |
| Sulfated Ash | Gravimetric Analysis | Ignition at 750 C followed by weighing of non-volatile inorganic residue after sulfuric acid treatment. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid transitions to liquid, using calibrated capillary method per USP <741>. |
| Acid Value | Acid-Base Titration | Neutralization of carboxylic acid groups with standardized NaOH solution using phenolphthalein indicator. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry or wet dispersed sample via light scattering to determine D10, D50, D90 values. |
| Bulk Density | Tap Density Measurement | Mass per unit volume measured after controlled tapping of a known mass in a graduated cylinder per USP <616>. |
| Microbial Limits | Membrane Filtration | Enumeration of aerobic microorganisms and absence testing for specified pathogens using culture-based filtration and incubation. |
Technical Specifications of 4,5-Difluorophthalic acid
| Test Item | Specification |
|---|---|
| Appearance | Off-white crystalline solid |
| Purity | >=98.0% (HPLC) |
| Melting Point | 192–196°C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4,5-Difluorophthalic acid
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4,5-Difluorophthalic acid
Packaging of 4,5-Difluorophthalic acid
Industrial 4,5-Difluorophthalic acid Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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