China Factory Direct
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| CAS number | 189628-38-4 |
| Product name | 5-FLUORO-2-METHOXYBENZONITRILE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty GradeElectronic GradeMaterial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pesticides | Synthesis of fluorinated pesticide intermediates | Serves as a key intermediate in aromatic ring substitution reactions for preparing fluorobenzonitrile-based herbicides or insecticides |
| Pharmaceuticals | Synthesis of active pharmaceutical ingredient (API) intermediates | Used to construct fluorinated aromatic structures as synthetic precursors for anticancer, antiviral, or central nervous system drugs |
| Dyes and Pigments | Synthesis of specialty dye intermediates | Introduces the fluoromethoxybenzonitrile structure via nucleophilic substitution or coupling reactions for high-performance organic pigment production |
| Electronic Chemicals | Synthesis of organic semiconductor material precursors | Serves as a fluorinated aromatic unit in polymerization or conjugated system construction for OLED or organic thin-film transistor materials |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at ~220–254 nm, comparing peak area against a certified reference standard. |
| Residual Solvents | GC-FID | Separation and quantification of volatile organic solvents (e.g., methanol, toluene, THF) using capillary GC with flame ionization detection and internal standard calibration. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration based on the reaction of iodine with water in anhydrous pyridine/methanol medium; measures trace water content precisely. |
| Heavy Metals (as Pb) | ICP-MS | Multi-element quantification of trace metals (Pb, Cd, Hg, As) after acid digestion, using inductively coupled plasma mass spectrometry for sub-ppt sensitivity. |
| Residual Catalyst (Pd) | ICP-OES | Quantification of palladium residues post-catalytic synthesis via microwave-assisted acid digestion followed by optical emission detection in plasma. |
| Related Substances | HPLC-DAD | Identification and quantification of structurally related impurities (e.g., 5-fluoro-2-hydroxybenzonitrile, des-methyl analogs) using HPLC with diode array detection and spectral library matching. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition measurement by observing solid-to-liquid phase change under controlled heating rate; verifies identity and crystallinity. |
| Chloride Impurity | Ion Chromatography (IC) | Separation and quantification of chloride ions using suppressed conductivity detection after aqueous extraction and filtration. |
| Appearance | Visual Inspection (against USP <941>) | Assessment of physical state, color, and clarity of solid sample in white-lighted environment per pharmacopeial guidelines. |
| Particle Size Distribution | Laser Diffraction | Measurement of size distribution of dry powder via Mie scattering theory analysis of laser light diffraction patterns. |
| Organic Volatile Impurities (OVI) | GC-MS | Confirmatory identification and quantification of unknown or low-level volatile impurities using gas chromatography coupled with mass spectrometric detection. |
| Sulfated Ash | Gravimetric Analysis | Determination of inorganic residue after controlled charring and sulfuric acid treatment, followed by high-temperature incineration and weighing. |
| Optical Rotation | Polarimetry | Measurement of specific rotation using sodium D-line light to detect chiral impurities or enantiomeric excess (if applicable to synthetic route). |
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 68–72°C |
| Identification (NMR) | Conforms to reference spectrum |
| Identification (IR) | Conforms to reference spectrum |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.