4-Methylumbelliferyl-beta-D-glucopyranoside Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 18997-57-4 |
| Product name | 4-Methylumbelliferyl-beta-D-glucopyranoside |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4-Methylumbelliferyl-beta-D-glucopyranoside
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4-Methylumbelliferyl-beta-D-glucopyranoside Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4-Methylumbelliferyl-beta-D-glucopyranoside
| Industry | Application | Process |
|---|---|---|
| Biomedical Research | Reagent for detecting β-glucuronidase activity | Enzymatic hydrolysis: In a pH 4.5–5.0 buffer system, the substrate is specifically hydrolyzed by β-glucuronidase to release highly fluorescent 4-methylumbelliferone (4-MU), enabling quantitative measurement of enzyme activity via fluorometric spectrophotometry (excitation at 365 nm, emission at 445 nm) |
| Clinical Diagnostics | Detection of β-glucuronidase activity in urine, tissue homogenates, or cell lysates for auxiliary screening of lysosomal storage disorders (e.g., Sanfilippo syndrome type B) | After sample pretreatment, the substrate is added and incubated at 37 °C for 30–60 min; the reaction is then terminated and fluorescence intensity measured, with enzyme activity calculated (nmol 4-MU/min/mg protein) against a standard curve |
| Microbiology | Rapid identification of Gram-negative bacteria such as Escherichia coli (some strains express β-glucuronidase) | The substrate is incorporated into selective chromogenic media (e.g., MacConkey agar or CHROMagar); positive colonies hydrolyze the substrate to produce blue fluorescence, enabling direct identification under 365 nm UV light |
| Drug Metabolism Studies | Evaluation of enzymatic stability of drug-glucuronide conjugates and kinetic profiling of coordinated metabolism by UGT and β-glucuronidase | Used as an internal standard or competitive substrate in in vitro hepatic microsomal or recombinant enzyme systems to monitor hydrolysis rate and correct for interference from endogenous β-glucuronidase |
Manufacturing Quality Control of 4-Methylumbelliferyl-beta-D-glucopyranoside
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main compound by UV absorption at specific wavelength using reverse-phase chromatography with external standard calibration. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities using gradient HPLC separation and UV detection. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., methanol, acetone) by gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Determines water content via coulometric or volumetric titration based on iodine-sulfur dioxide redox reaction. |
| Heavy Metals | ICP-MS | Quantifies trace metal contaminants (e.g., Pb, Cd, Hg) by inductively coupled plasma mass spectrometry after acid digestion. |
| Chloride Impurity | Ion Chromatography | Separates and quantifies chloride ions using anion-exchange column and conductivity detection. |
| Sulfate Impurity | Ion Chromatography | Separates and quantifies sulfate ions using anion-exchange column and conductivity detection. |
| Residue on Ignition | Gravimetric Analysis | Measures non-volatile inorganic residue after high-temperature ashing and weighing. |
| Appearance | Visual Inspection | Assesses physical state, color, and clarity of solid sample against established reference standards. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid using calibrated capillary method. |
| Specific Optical Rotation | Polarimetry | Measures chiral purity by detecting rotation of plane-polarized light in solution at specified concentration and wavelength. |
| Microbial Contamination | Membrane Filtration | Detects aerobic microorganisms by filtration, membrane transfer to culture media, and colony enumeration. |
Technical Specifications of 4-Methylumbelliferyl-beta-D-glucopyranoside
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Melting Point | 198°C - 202°C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.1% |
| Optical Rotation | -20° to -24° (c=1, in methanol) |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4-Methylumbelliferyl-beta-D-glucopyranoside
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4-Methylumbelliferyl-beta-D-glucopyranoside
Safety Information of 4-Methylumbelliferyl-beta-D-glucopyranoside
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 4-Methylumbelliferyl-beta-D-glucopyranoside
Industrial 4-Methylumbelliferyl-beta-D-glucopyranoside Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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