China Factory Direct
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| CAS number | 190728-25-7 |
| Product name | 4-((6,7-Dimethoxyquinolin-4-yl)oxy)aniline |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate for anticancer drugs (e.g., tyrosine kinase inhibitors) | Used in organic synthesis and coupling reactions |
| Chemicals | Fine chemical raw material | Applied in multi-step synthesis processes |
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the sample's color, physical state, and visible impurities under natural light or standard illumination. |
| Identification | Infrared Spectroscopy (IR) | Determine the infrared absorption spectrum of the sample and compare it with reference standards or known spectra to confirm functional groups and structural characteristics. |
| Proton Nuclear Magnetic Resonance (¹H-NMR) | Utilize ¹H-NMR to analyze chemical shifts, coupling patterns, and splitting of hydrogen atoms for verification of molecular structure. | |
| High-Performance Liquid Chromatography-Mass Spectrometry (HPLC-MS) | Confirm molecular ion peaks and fragment ions based on retention time and mass-to-charge ratio (m/z), aiding in structural elucidation. | |
| Purity/Content Determination | High-Performance Liquid Chromatography (HPLC) | Use reversed-phase HPLC (e.g., C18 column) with UV detection (typically at 254–365 nm), and calculate main component content using external standard or area normalization methods. |
| Impurity Testing | HPLC Method (Related Substances) | Separate the active ingredient from impurities using gradient elution; detect degradation products and synthesis by-products. Typically, individual impurities should be ≤0.5%, and total impurities ≤2.0%. |
| Residual Solvents | Gas Chromatography (GC) | Follow ICH guidelines to detect potentially residual organic solvents (e.g., methanol, ethanol, dichloromethane, DMF) from manufacturing processes. |
| Moisture Content | Karl Fischer Titration | Determine water content using coulometric or volumetric Karl Fischer methods, suitable for quality control of moisture-sensitive active pharmaceutical ingredients. |
| Melting Point | Melting Point Determination | Measure the temperature range at which a compound transitions from solid to liquid using a melting point apparatus, useful for identification and purity assessment. |
| Heavy Metals | Heavy Metal Test (Pharmacopoeia Method) | Detect heavy metal residues such as lead, cadmium, mercury, and arsenic using thioacetamide method or inductively coupled plasma mass spectrometry (ICP-MS). |
| Residue on Ignition | Sulfate Ash Method | Calcine the sample at high temperature and weigh the residue to assess inorganic impurity levels. |
| Polymorphic Analysis (if applicable) | X-Ray Powder Diffraction (XRPD) | Analyze the crystalline structure of solid samples for polymorph control, ensuring batch-to-batch consistency. |
| Particle Size Distribution (if applicable) | Laser Particle Size Analysis | Evaluate particle size distribution of raw materials, which affects dissolution rate and formulation performance. |
| Test Item | Specification |
|---|---|
| Appearance | Brown solid |
| Purity | >=98.0% (LC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 178–182°C |
| Identification (NMR) | Conforms to reference spectrum |
| Heavy Metals | <=20 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.