1914-65-4 Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 1914-65-4 |
| Product name | 1914-65-4 |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 1914-65-4
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 1914-65-4 Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 1914-65-4
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key chiral intermediate for the synthesis of the antiplatelet drug ticagrelor | Chiral resolution or asymmetric synthesis of (S)-1,2,3,4-tetrahydronaphthalene-1-carboxylic acid, followed by amide formation, coupling, and other sequential reactions to construct the core structure of ticagrelor |
| Pharmaceuticals | Structural modification precursor for naproxen derivatives and novel COX-2 inhibitors | Introduction of substituents via functional group transformations—including esterification, halogenation, and Suzuki coupling—to optimize pharmacological activity and metabolic stability |
| Organic Synthesis | Building block for chiral ligands and catalysts | Conversion to 1,2,3,4-tetrahydronaphthalene-1-carbonyl chloride, followed by condensation with chiral amino alcohols to prepare novel chiral amide ligands for asymmetric hydrogenation |
Manufacturing Quality Control of 1914-65-4
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | Acid-Base Titration with NaOH | Quantifies carboxylic acid group via neutralization with standardized sodium hydroxide solution using phenolphthalein or potentiometric endpoint detection. |
| Water Content | Karl Fischer Titration | Measures water by iodine oxidation of sulfur dioxide in pyridine/methanol medium, where water is stoichiometrically consumed. |
| Residue on Ignition | Gravimetric Analysis | Determines non-volatile inorganic impurities by high-temperature ashing followed by weighing of residual ash. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) | Quantifies trace metal contaminants (e.g., Pb, Cd, Hg) by measuring absorption of element-specific UV-Vis radiation in atomized sample vapor. |
| Chloride Impurity | Ion Chromatography (IC) | Separates and quantifies chloride ions using anion-exchange column with conductivity detection. |
| Related Substances | High Performance Liquid Chromatography (HPLC) | Separates and quantifies structurally similar impurities using reversed-phase C18 column and UV detection at 220–254 nm. |
| Melting Point | Capillary Melting Point Determination | Measures temperature range at which solid transitions to liquid using calibrated capillary apparatus under controlled heating rate. |
| Specific Optical Rotation | Polarimetry | Determines chiral purity by measuring rotation angle of plane-polarized light passing through a solution of the compound. |
| Appearance | Visual Inspection | Assesses physical state, color, and clarity against established reference standards under controlled lighting conditions. |
| Solubility | Qualitative Solubility Test | Evaluates dissolution behavior in specified solvents (e.g., ethanol, methanol, water) per pharmacopeial or internal specifications. |
| pH of Aqueous Suspension | pH Meter Measurement | Measures hydrogen ion activity in a defined suspension (e.g., 1% w/v in water) using calibrated pH electrode. |
| Volatile Organic Impurities | Gas Chromatography (GC) with FID | Separates and quantifies low-boiling organic residues using capillary column and flame ionization detection. |
Technical Specifications of 1914-65-4
| Test Item | Specification |
|---|---|
| Appearance | White to light yellow crystalline powder |
| Purity | >=98.0% (LC-MS) |
| Melting Point | 124–128°C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Acid Value (mg KOH/g) | 185–195 mg KOH/g |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 1914-65-4
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 1914-65-4
Packaging of 1914-65-4
Industrial 1914-65-4 Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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